Monensin amides for sodium-selective electrodes

Chemistry: electrical and wave energy – Apparatus – Electrolytic

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204403, 204416, 204430, 252 622, 252500, 549334, G01N 2726

Patent

active

055229786

ABSTRACT:
This invention relates to sodium-selective agents which are monensin amide derivatives and sodium-selective electrodes having sodium-selective membranes containing such monensin amide derivatives. This invention further relates to multisensor flow assemblies incorporating such a monensin amide derivative in a sodium-selective electrode.

REFERENCES:
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patent: 5284568 (1994-02-01), Pace et al.
Maruyama et al., Enantiomer Recognition of Organic Ammonium Salts by Podadn and Crown Type Monesin Amides: New Synthetic Strategy for Chiral Receptors, pp. 805-805, Tetrahedron vol. 48, No. 5, 1992.
Brandchaud, B. P., and Choi, Y. C., Synthesis of Monensin. Reconstruction from Degradation Products, J. Org. Chem. 53, 4641-4643, 1988.
Kimura, K. et al., Unsymmetrical Calix[4]Arene Ionophore/Silicone Rubber Composite Membranes for High-Performance Sodium Ion-Sensitive Field-Effect Transistors, Anal. Chem., 64, 2508-2511, 1992.
Lehn, Jean-Marie, Supramolecular Chemistry: Receptors, Catalysts, and Carriers, Science, 227, No.4689, 849-856, Feb. 22, 1986.
Maruyama, K., et al., New Chiral Host Molecules Derived from Naturally Occurring Monensin Ionophore, J. Chem. Soc., Chem. Commun., 864-865, 1989.
Maruyama, K., et al., Enantiomer Recognition of Organic Ammonium Salts by Podand-And Crown-Type Monensin Amides: New Synthetic Strategy for Chiral Receptors, Tetrahedron, 48, No. 5, 805-818, 1992.
Suzuki, K., et al., Ion-Selective Electrodes Based on Natural Carboxylic Polyether Antibiotics, Anal. Chem., 60, 1714-1721, 1988.
Tamura, H., et al., Coated Wire Sodium-and Potassium-Selective Electrodes Based on Bis(crown ether) Compounds, Anal. Chem., 54, 1224-1227, 1982.
Tohda, K., et al., A Sodium Ion Selective Electrode Based on a Highly Lipophilic Monensin Derivative and Its Application to the Measurement of Sodium Ion Concentrations in Serum, Analytical Sciences, 6, 227-232, Apr. 1990.

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