Non-lytic baculovirus

Details Non-lytic baculovirus Non-lytic baculovirus

2007-05-29

2007-05-29

Guzo, David (Department: 1636)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S235100, C435S320100

Reexamination Certificate

active

10775050

ABSTRACT:
A baculovirus that infects a host cell without lyzing the host cell and related protein expression method. Within the scope of this invention are in vitro and in vivo methods for detecting protein folding or a cell lysis activity of a sample. Also within the scope of this invention is a method of screening for a compound for treating a disease associated with misfolding of a protein.

REFERENCES:
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G. S. Lakshmikanth et al. “Structure is lost incrementally during the infolding of barstar”. Nature Structural Biology 8(9):799-804, Sep. 2001.
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Z. Serber et al. “In-Cell NMR Spectroscopy”. Biochemistry 40(48):14317-14323, Dec. 4, 2001.

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