Process for the racemization of N-protected amino acids...

Details Process for the racemization of N-protected amino acids... Process for the racemization of N-protected amino acids...

2007-01-02

2007-01-02

Saucier, Sandra E. (Department: 1651)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

C435S107000, C435S108000, C435S109000, C435S110000, C435S113000, C435S114000, C435S116000

Reexamination Certificate

active

10651938

ABSTRACT:
The present invention relates to the processes of racemization and deprotection of special N-protected amino acids in the acylase/racemase system for the total conversion of special N-protected racemic amino acids into optically pure amino acids.

REFERENCES:
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patent: 1 074 628 (2001-02-01), None
Tokuyama S. 2001. Discovery and application of a new enzyme N-acylamino acid racemase. J Mol Catalysis B 12: 3-14.
Verseck S et al. 2001. Screening, overexpression, and characterization of an N-acylamino acid racemase from Amycolatopsis orientalis subsp. lurida. Appl Microbiol Biotechnol 55: 354-361.
Tokuyama S et al. 1995. Purification and properties of thermostable N-acylamino acid racemase from Amycolatopsis sp. TA-1-60. Appl. Microbiol Biotechnol 42: 853-859.

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