2-[[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-(piperidinyl or

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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260281NH, 260281S, 260295K, 2602936, A61K 31645, A61K 3147, C07D40114

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039963624

ABSTRACT:
Compounds of the following formula and their acid addition salts ##STR1## wherein R.sup.1 and R.sup.2 are selected from hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, amino, trifluoromethyl, or cyano; R.sup.3 is hydrogen or lower alkyl; R.sup.4 and R.sup.5 are selected from hydrogen, halogen, lower alkyl, or lower alkoxy; the dashed line indicates the optional presence of a double bond; and A is straight or branched chain alkylene of 1-8 carbons; are disclosed. These compounds exhibit antidepressant activity. In addition, these compounds are useful as antiinflammatory agents.

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Kimura et al. Chem. Abs. 62, 11950c(1964).

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