Desaturase genes and uses thereof

Details Desaturase genes and uses thereof Desaturase genes and uses thereof

2007-07-10

2007-07-10

Sullivan, Daniel M. (Department: 1636)

Chemistry: molecular biology and microbiology

Plant cell or cell line, per se ; composition thereof;...

C435S254110, C435S320100, C435S071100, C536S023100, C536S023200

Reexamination Certificate

active

10431952

ABSTRACT:
The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., “Δ5-desaturase”) and at carbon 6 (i.e., “Δ6-desaturase”) and to uses thereof. In particular, Δ5-desaturase may be utilized, for example, in the conversion of dihomo-γ-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20:4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to γ-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.

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