Spirotricyclic derivatives and their use as...

Details Spirotricyclic derivatives and their use as... Spirotricyclic derivatives and their use as...

2007-05-08

2007-05-08

O'Sullivan, Peter (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S252150, C514S266300, C514S266310, C544S070000, C544S231000

Reexamination Certificate

active

10852404

ABSTRACT:
The invention provides compounds which are PDE7 inhibitors, having the following formula (I), (II) and (III)in which X1, X2, X3, X4, X, Y, Z, A and Z1are as defined in the description, methods for preparing them and their use for the treatment of disorders for which therapy by a PDE7 inhibitor is relevant.

REFERENCES:
patent: 5536716 (1996-07-01), Chen et al.
patent: 5578593 (1996-11-01), Chen et al.
patent: 5652235 (1997-07-01), Chen et al.
patent: 6358948 (2002-03-01), Zhang et al.
patent: 6693103 (2004-02-01), Zhang et al.
patent: 0 070 171 (1983-01-01), None
patent: WO 00/66560 (1920-11-01), None
patent: WO 88/01508 (1988-03-01), None
patent: WO 1994/13696 (1994-06-01), None
patent: WO 1994/19367 (1994-09-01), None
patent: WO 1997/14686 (1997-04-01), None
patent: WO 00/66164 (2000-11-01), None
patent: WO 00/66570 (2000-11-01), None
patent: WO 00/66571 (2000-11-01), None
patent: WO 2000/66165 (2000-11-01), None
patent: WO 2001/45707 (2001-06-01), None
Takai et al., Chemical Abstracts, vol. 111:7312, 1989.
Teranishi et al., Chemical Abstracts, vol. 99:70751, 1983.
Carretero, Juan C., et al., “A Practical Route to C-8 Substituted Fluoroquinolones”, Tetrahedron, vol. 48, No. 32, 1992, pp. 7373-7382.
H. Takai, et al., “Cyclofunction alization of Olefinic Urethanes and Ureas with Halogens. Synthesis of 1-2ubstituted spiro[piperidine-4,4′(3′H)-quinazolun]-2′(1′H)-one derivatives”, Chem Pharm. Bull., 1998 pp. 4659-4670, vol. 36, No. 12.

Affiliated with

Also associated with

Rating

Spirotricyclic derivatives and their use as... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Spirotricyclic derivatives and their use as..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Spirotricyclic derivatives and their use as... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3800532