Method for treating inflammatory bowel diseases

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

Reexamination Certificate

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Reexamination Certificate

active

10740675

ABSTRACT:
The present invention relates to a method for treating an inflammatory bowel disease, including administering an effective amount of 1,4-dihydroxy-2-naphthoic acid or a salt thereof.

REFERENCES:
patent: 2004/0241815 (2004-12-01), Sato et al.
patent: 2005/0137261 (2005-06-01), Okada et al.
The Merck Manual, 17thedition, 1999, pp. 302-312, & 313.
Yoshikiyo Okada, et al. “Studies of Antiinflammatory Effect of DHNA, a Component of Whey Fermentation Product, Produced by Propionic Acid Bacterium on DSS Enteritis”, 40th Annual Meeting of Japanese Society for Mucosal Immunology, Aug. 7 and 8, 2003, 3 pgs (with Translation).
Yoshikiyo Okada “Studies of Antiinflammatory Effect of DHNA, a Component of Whey Fermentation Product, Produced by Propionic Acid Bacterium on DSS Enteritis”, The 89th Annual Meeting of the Japanese Society of Gastroenterology, Apr. 24 to 26, 2003, 5 pgs (with Translation).
Y. Okada, et al., “Propionibacterium freudenreichiiComponent 1.4-Dihydroxy-2-Naphthoic Acid (DHNA) Attenuates Dextran Sodium Sulphate Induced Colitis by Modulation of Bacterial Flora and Lymphocyte Homing”, Gut 2006:55:681-688.

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