Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-05-08
2007-05-08
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S408000, C514S410000, C514S412000, C548S416000, C548S452000, C548S453000
Reexamination Certificate
active
10771756
ABSTRACT:
Disclosed are compounds of formula (I):or stereoisomers or pharmaceutically acceptable salts thereof, wherein the groups Ar1, Ar2, A, R1, R2, R3, E1, E2, X and n are as defined in the description and claims, which are effective modulators of chemokine activity.
REFERENCES:
Molina, Pedro et al; Inhibition of Leucocyte functions by the alkalols isaindigotone from Isatis indigotica and some new synthetic derivatives, Journal of Natural Products, vol. 64, No. 10, 2001, XP002286635, example 1.
Rioja, Immaculada, et al; “A pyrroloquinazoline derivative with antiinflammatory and analgesic activity by dual inhibition of COX-2 and 5-lipooxygenase” European Journal of Pharmacology, vol. 434, No. 10, 2002, XP 002286636 figures, example 1.
Anderskewitz Ralf
Birke Franz
Bouyssou Thierry
Dollinger Horst
Heine Claudia
Boehringer Ingelheim International GmbH
Bottino Anthony P.
Devlin Mary-Ellen M.
Morris Michael
Ward Paul V.
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