DNA sequence and recombinant production of a Gramineae allergen

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Allergen or component thereof

Reexamination Certificate

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Details

C530S370000, C530S379000, C536S023600

Reexamination Certificate

active

09959340

ABSTRACT:
The invention relates to the identification and characterization of a grass-pollen allergen, and to the recombinant DNA molecule encoding therefore, and to corresponding DNA and peptide sequences.

REFERENCES:
patent: 5869333 (1999-02-01), Singh et al.
Suck et al., Journal of Immunological Methods, vol. 229, pp. 73-80, 1999.
Lockey et al. Allergens and Allergen Immunotherapy. 2004. The Second Edition published by Marcel Dekker, Inc. pp. 37-50.
Schramm et al. The Journal of Immunology. 1999. 162:2406-2414.
Niogret et al.: Characterization of pollen polygal acturonase encoded by several cDNA clones in maize. Plant Molecular Biology, vol. 17, No. 6, Dec. 1991, pp. 1155-1164, XP002151351.
Suck et al.: Complementary DNA cloning and expression of a newly recognized high molecular mass allergen Phl p 13 from timothy grass (Phleum pratense) Clinical and Experimental Allergy, vol. 30, No. 3, Mar. 2000, pp. 324-332, XP000 953168.
Fisher et al.: Charaterization of Phl p4, a major timothy grass (Phleum pratense) pollen allergen, The Journal of Allergy and Clinical Immunology, vol. 98, No. 1, Jul. 1998, pp. 189-198, XP000953216.
Vrtala et al.: Immunologic characterization of purified recombinant timothy grass pollen (Phleum pratense) allergens (Phl p 1, Phl p2, Phl p5), The journal of allergy and clinical immunology, vol. 97, No. 3, Mar. 1996, pp. 781-787, XP000953173.

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