Pyrrolidine derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S530000, C548S539000, C548S541000, C548S542000, C514S424000, C514S425000

Reexamination Certificate

active

10881427

ABSTRACT:
The present invention relates to pyrrolidine derivatives useful as inhibitors of metalloproteases, e.g. zinc proteases, and which are effective in treating disease states associated with vasoconstriction.

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Chemical Abstract, “Synthesis and antimicrobial evaluation of 3-(substituted)pyrrolidine cephalosporins”, (Yoo, Ji-Seak et al., JP) (1999).

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