Three-dimensional structure of polyketide synthases

Details Three-dimensional structure of polyketide synthases Three-dimensional structure of polyketide synthases

2007-05-15

2007-05-15

Nashed, Nashaat T. (Department: 1656)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Lyase

C435S183000

Reexamination Certificate

active

10031918

ABSTRACT:
The present invention comprises crystalline polyketide synthases, isolated non-native polyketide synthases having the structural coordinates of said crystalline polyketide synthases, and nucleic acids encoding such non-native polyketide synthases. Also disclosed are methods of predicting the activity and/or substrate specificity of putative polyketide synthase, methods of identifying potential polyketide synthase substrates, and methods of identifying potential polyketide synthase inhibitors.

REFERENCES:
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