Metal complex compounds

Details Metal complex compounds Metal complex compounds

2007-04-03

2007-04-03

Nazario-Gonzalez, Porfirio (Department: 1621)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

C424S009360, C424S009363, C534S013000, C534S016000, C546S002000

Reexamination Certificate

active

10496852

ABSTRACT:
The invention relates to metal complex compounds, contrast agents for MRI and in vivo NMR markers for NMR spectroscopy comprising said metal complex compounds and methods for in vivo determination of physiological parameters, e.g. enzyme activity or pH using said metal complex compounds.

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Watson, A.D., Rocklage, S. M. and Carvlin, M. J.: Contrast agents in Stark, D. D. and Bradley, W. G. (Eds.):Magnetic resonance imaging. vol. One. Mosby Year Book. St. Louis (1992) 372-437.
Berger et al. (Eds.), NMR Spectroscopy of the non-metallic elements, John Wiley & Sons, Chichester 1997, Chapter 6, p. 398-699.
International Search Report for PCT/NO02/00453 dated Apr. 7, 2003.

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