Compositions for identification and isolation of stem cells

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S007230, C435S091500, C435S021000, C435S028000, C435S069100, C435S070210, C435S330000, C435S975000, C436S512000, C436S548000, C436S172000, C436S804000, C530S387300, C530S388200, C530S388800, C530S391300, C530S391700

Reexamination Certificate

active

10315492

ABSTRACT:
The invention provides monoclonal antibodies that selectively bind to ectodermally- and endodermally-derived stem cells and methods for the diagnosis of a neoplasm in a subject by contacting a tissue sample from the subject with the antibodies. Also disclosed are methods for isolating such stem cells from a heterogeneous cell population by contacting the population with antibodies which selectively bind to stem cells.

REFERENCES:
patent: 4714680 (1987-12-01), Civin
patent: 5061620 (1991-10-01), Tsukamoto et al.
patent: 5087570 (1992-02-01), Weissman et al.
patent: 5486359 (1996-01-01), Caplan et al.
patent: 5548065 (1996-08-01), Lemischka
patent: 5773224 (1998-06-01), Grandics et al.
patent: 5789246 (1998-08-01), Reid et al.
patent: 5861313 (1999-01-01), Pang et al.
patent: 6258939 (2001-07-01), Reiter et al.
patent: 6632620 (2003-10-01), Makarovskiy
patent: WO 92 14821 (1992-09-01), None
patent: WO 92/18643 (1992-10-01), None
patent: WO 92/22584 (1992-12-01), None
patent: WO 93/25216 (1993-12-01), None
patent: WO 96/15229 (1996-05-01), None
patent: WO 96/22693 (1996-08-01), None
patent: WO 96/40875 (1996-12-01), None
patent: WO 98/00523 (1998-01-01), None
patent: WO 98 40403 (1998-09-01), None
patent: WO 99/23205 (1999-05-01), None
patent: WO 99/61584 (1999-12-01), None
patent: WO 99/61587 (1999-12-01), None
Kubota, et al., Clonogenic hepatoblasts, common precursors for hepatocytic and biliary lineages, are lacking classical major histocompatibility complex class I antigen, Proc. Natl. Acad. Sci. USA 97(22):12132-37 (2000).
LeDouarin, Cell Line Segregation During Peripheral Nervous System Ontogeny,Science231:1515-22 (1986).
Novikoff, et al., Stem Cells and Rat Liver Carcinogenesis: Contributions of Confocal and Electron Microscopy, Journal of Histochemistry & Cytochemistry 46: 613-26 (1998).
Sakurai, et al., Journal of Surgical Oncology 42:39-46 (1989).
Saati, et al., Blood, 74:2476-2485 (1989).
Makarovskiy, et al. “Comparative immunohistochemical analysis of normal and neoplastic prostate tissues using novel markers,”Proc of the American Association.39:201, Mar. 1998abstract.
Halpert, et al. “Development of normal and SV40-large T immortalized dorsal-lateral rat prostate cell lines”.Proc of the American Association for Cancer Research Annual Meeting, 37:508-509, 1996,abstract.
Uchida et al. “Direct Isolation of Human Neural Stem Cells From Fetal Brain By Cell Sorting”,Society for Neuroscience Abstracts, 25 1-2:ABS70103, 1993,abstract.
Gu et al. “Monoclonal Antibodies Against Prostate Stem Cell Antigen (PSCA) Detect High Levels of PSCA Expression in Prostate Cancer Bone Metastates”Journal of Urology, 161 4,:126, 1999,abstract.
Ware et al., 1982. Production of monoclonal antibody αPro3 recognizing a human prostatic carcinoma antigen. Cancer Research 42: 1215-1222.
Stemple et al., 1992. Isolation of a stem cell for neurons and glia from the mammalian neural crest. Cell 71:973-985.
Zhau et al., 1992. Expression of c-erbB-2
euproto-oncogene in human prostatic cancer tissues and cell lines. Molecular Carcinogenesis 5: 320-327.
Lo et al., 1995. Postmigratory neural crest cells expressing c-RET display restricted developmental and proliferative capacities. Neuron 15: 527-539.
Rokhlin et al., 1998. 5E10: a prostate-specific surface reactive monoclonal antibody. Cancer Letters 131: 129-136.
Bodey et al., 1996. Identification of neural crest derived cells within the cellular microenvironment of the human thymus employing a library of monoclonal antibodies raised against neuronal tissues. In Vivo 10: 39-48.
Trikha et al., 1996. Human prostate carcinoma cells express functional allbβ3 integrin. Cancer Research 56: 5071-5078.
Rao et al., 1997. Immortalization and controlled in vitro differentiation of murine multipotent neural crest stem cells. J. Neurobiology 32: 722-746.

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