Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Reexamination Certificate
2007-07-17
2007-07-17
Tucker, Zachary C. (Department: 1624)
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
C546S113000, C546S118000, C546S122000, C546S141000, C560S012000, C560S027000
Reexamination Certificate
active
10981120
ABSTRACT:
The present invention relates to the novel methods of making matrix metalloproteinase inhibitors of Formula (I):
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Kenyon and Young, “Constitution of the alcohol (δ-methyl-δ-penten-β-ol) previously resolved and described as α,γ,γ-trimethylallyl alcohol” Journal of the Chemical Society, pp. 1452-1454 (1938) as Abstracted by STN-Caplus.
Arcus and Kenyon, “Reduction of the carbonyl group in unsaturated ketones and the interconversion of geometrical isomerides during such reduction” Journal of the Chemical Society, pp. 698-699 (1938) as Abstracted by STN-Caplus.
Kenyon and Young, “Composition of the Ponndorff-Meerwein reduction product of mesityl oxides” Journal of the Chemical Society, pp. 1547-1550 (1940) as Abstracted by STN-Caplus.
Crombie and Harper, “Synthesis and configuration of (+)-6-methyloctanoic acid, a degradation product of the polymyxins” Journal of the Chemical Society, pp. 2685-2689 (1950) as Abstracted by STN-Caplus.
Crombie and Harper, “‘Leaf alcohol’ and the stereochemistry of the cis- and trans-3-hexen-1-ols and -3-penten-1-ols” Journal of the Chemical Society, pp. 873-877 (1950) as Abstracted by STN-Caplus.
Crombie, “Amides of vegetable origin. I. Stereoisomeric N-isobutyl-1,7-hendecadien-1-carboxyamides and the structure of herculin” Journal of the Chemical Society,.pp. 2997-3008 (1952) as Abstracted by STN-Caplus.
Crombie, “Amides of vegetable origin. II. Stereoisomeric N-isobutyl-1,5-nonadien-1-carboxamides and the structure of pellitorine” Journal of the Chemical Society, pp. 4338-4346 (1952) as Abstracted by STN-Caplus.
van Gelderen, “Reactions of 4-biphenyl isocyanate with alcohols and amino compounds” Recueil des Travaux Chimiques des□□ Pay-Bays et de la Belgique, vol. 52, pp. 969-975 (1933).
Morgan et al, “Production of higher alcohols, aldehydes and ketones” Chemistry & Industry, pp. 518-519 (1933).□□.
Simonsen and Gillam, “α-Cyperone, a sesquiterpene ketone from the oil ofCyperus rotundus” Journal of the Chemical Society,□□pp. 667-677 (1936).
Kenyon and Young, “Constitution of the alcohol (5-methyl-6-penten-13-ol) previously resolved and described as α,γ,γ-trimethylallyl alcohol” Journal of the Chemical Society, pp. 1452-1454 (1938).
Arcus and Kenyon, “Reduction of the carbonyl group in unsaturated ketones and the interconversion of geometrical isomerides during such reduction” Journal of the Chemical Society, pp. 698-699 (1938).
Kenyon and Young, “Composition of the Ponndorff-Meerwein reduction product of mesityl oxides” Journal of the Chemical Society, pp. 1547-1550 (1940).
Crombie and Harper, “Synthesis and configuration of (+)-6-methyloctanoic acid, a degradation product of the polymyxins” Journal of the Chemical Society, pp. 2685-2689 (1950).
Crombie and Harper, “‘Leaf alcohol’ and the stereochemistry of the cis- and trans-3-hexen-I-ols and -3-penten-I-ols” Journal of the Chemical Society, pp. 873-877 (1950).
Crombie, “Amides of vegetable origin. I. Stereoisomeric N-isobutyl-l,7-hendecadien-I-carboxyamides and the structure of herculin” Journal of the Chemical Society,.pp. 2997-3008 (1952).
Crombie, “Amides of vegetable origin. II. Stereoisomeric N-isobutyl-l,5-nonadien-I-carboxamides and the structure of pellitorine” Journal of the Chemical Society, pp. 4338-4346 (1952).
Greene, et al., Silyl Esters, Protective Groups in Organic Chemistry; Wiley, New York, 1991; Chapter 5; pp. 261-263.
Larock, R.C., Interconversion of Nitriles, Carboxylic Acids and Derivatives, Comprehensive Organic Transformations: A Guide to Functional Group Preparations, VCH Publishers, New York, Weinheim; 1999; pp. 1929-1930.
March, et al., Aromatic Electrophilic Substitution, March's Advanced Organic Chemistry: Reactions, Machanisms, adn Structure; Wiley, New York, 2001; pp. 702-704.
Ort Ronald G.
Sanofi-Aventis Deutschland GmbH
Tucker Zachary C.
LandOfFree
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