Process for preparing benzodiazepines

Details Process for preparing benzodiazepines Process for preparing benzodiazepines

1975-06-02

1976-12-07

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260295Q, 260295S, 260295R, 260562N, 260999, C07D24328, C07D40104

Patent

active

039962091

ABSTRACT:
1,4-Benzodiazepin-2-ones are prepared via the reaction of a haloacetamidophenyl ketone with hexamethylenetetramine in the presence of ammonia. The 1,4-benzodiazepin-2-ones so prepared are known compounds useful as muscle relaxant and anti-convulsant agents.

REFERENCES:
patent: 3886141 (1975-05-01), Chase
Blazevic et al. I. "J. Het. Chem." vol. 7 pp. 1173-1174 (1970).
Blazevic et al. II "J. Het. Chem." vol. 9 pp. 531-537 (1972).

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