Composition comprising methylphenidate and another drug

Details Composition comprising methylphenidate and another drug Composition comprising methylphenidate and another drug

2007-09-11

2007-09-11

Salimi, Ali R. (Department: 1648)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C424S009100, C514S649000

Reexamination Certificate

active

10277413

ABSTRACT:
A process of treating a subject that is undergoing methylphenidate therapy and concomitant therapy with another drug undergoes or interferes with P450metabolism, wherein the methylphenidate is d-threo-methylphenidate.

REFERENCES:
patent: 2407631 (1946-09-01), Hartmann et al.
patent: 2838519 (1958-06-01), Rometsch
patent: 2957880 (1960-10-01), Rometsch
patent: 4192827 (1980-03-01), Mueller et al.
patent: 5583140 (1996-12-01), Bencherif et al.
patent: 5733756 (1998-03-01), Zeitlin et al.
patent: 5874090 (1999-02-01), Baker et al.
patent: 5908850 (1999-06-01), Zeitlin et al.
patent: 5922736 (1999-07-01), Dariani et al.
patent: 6255325 (2001-07-01), Dariani et al.
patent: 6355656 (2002-03-01), Zeitlin et al.
patent: 6486177 (2002-11-01), Zeldis et al.
patent: 6531489 (2003-03-01), Harris et al.
Aoyama, T. et al. “Pharmacokinetics and Pharmacodynamics of (+)-threo-Methylphenidate Enantiomer in Patients with Hypersomnia”Clinical Pharmacology&Therapeutics, 1994, pp. 270-276, vol. 55, No. 3.
Ariens, E. J. “Stereoselectivity in Pharmacodynamics and Pharmacokinetics”Schweiz. Med. Wochenschr., 1990, pp. 131-134, vol. 120, No. 5.
Ariens, E. J. “Racemic Therapeutics-Ethical and Regulatory Aspects”Eur. J. Clin. Pharmacol., 1991, pp. 89-93, vol. 41.
Drimmer, E. J. et al., “Desipramine and Methylphenidate Combination Treatment for Depression: Case Report”Am. J. Psychiatry, 1983, pp. 241-242, vol. 140, No. 2, **abstract only.
Eckerman, D. A. et al. “Enantioselective Behavioral Effects of threo-Methylphenidate in Rats”Pharmacology Biochemistry&Behavior, 1991, pp. 875-880, vol. 40, No. 4.
Grob, C. S. et al. “Suspected Adverse Methylphenidate-impipramine Interactions in Children”J. Dev. Behav. Pediatr., 1986, pp. 265-267, vol. 7, No. 4, **abstract only.
Licamele, W. L. et al. “The Concurrent Use of Lithium and Methylphenidate in a Child”J. Am. Acad. Child Adolesc. Psychiatry, 1989, pp. 785-787, vol. 28, No. 5, **abstract only.
Patrick, K. S. et al. “Pharmacology of the Enantiomers of the threo-Methylphenidate”The Journal of Pharmacology and Experimental Therapeutics, 1987, pp. 152-158, vol. 241, No. 1.
Rapport, M. D. et al. “Methylphenidate and Desipramine in Hospitalized Children: I. Separate and Combined Effects on Cognitive Function”J. Am. Acad. Child. Adolesc. Psychiatry, 1993, pp. 333-342, vol. 32, No. 2, **abstract only.
Tyndale, R. F. et al. “Neuronal Cytochrome P450IID1 (Debrisoquine/Sparteine-Type): Potent Inhibition of Activity by (-)-Cocaine and Nucleotide Sequence Identity to Human Hepatic P450 Gene CYP2D”Molecular Pharmacology, An International Journal, 1991, pp. 63-68, vol. 40, No. 1.
Aoyama, T. et al. “Nonlinear kinetics of threo-methylphenidate enantiomers ina patient with narcolepsy and in healthy volunteers”Eur. J. Clin. Pharmacol, 1993, pp. 79-84, vol. 44.
Barnes, N. M. et al. “THe interaction of R(+)-and S(−)-zacopride with PCPA to modify rodent aversive behaviour”European Journal of Pharmacology, 1992, pp. 15-25, vol. 218.
Ding, Y.-S. et al. “Chiral drugs: comparison of the pharmacokinetics of [11C]d-threo and l-threo-methylphenidate in the human and baboon brain”Psychopharmacology, 1997, pp. 71-78, vol. 131.
Hubbard, J. W. et al. “Enantioselective Aspects of the Disposition of dl-threo-Methylphenidate after the administration of a sustained-release formulation to children with attention deficit-hyperactivity disorder”Journal of Pharmaceutical Sciences, 1989, pp. 944-947, vol. 78, No. 11.
Srinivas, N. R. et al. “Enantioselective pharmacokinetics and pharmacodynamics of dl-threo-methylphenidate in children with attention deficit hyperactivity disorder”Clin. Pharmacol. Ther., 1992, pp. 561-568, vol. 52, No. 5.
Srinivas, N. R. et al. “Enantioselective Pharmacokinetics of dl-threo-Methylphenidate in Humans”Pharmaceutical Research, 1993, pp. 14-21, vol. 10, No. 1.

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