Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-04-03
2007-04-03
Henley, III, Raymond J. (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
Reexamination Certificate
active
11101369
ABSTRACT:
Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain sulfonamide or sulfonamide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
REFERENCES:
patent: 3314941 (1967-04-01), Littell et al.
patent: 4689338 (1987-08-01), Gerster
patent: 4698348 (1987-10-01), Gerster
patent: 4929624 (1990-05-01), Gerster et al.
patent: 4988815 (1991-01-01), Andre et al.
patent: 5037986 (1991-08-01), Gerster
patent: 5175296 (1992-12-01), Gerster
patent: 5238944 (1993-08-01), Wick et al.
patent: 5266575 (1993-11-01), Gerster
patent: 5268376 (1993-12-01), Gerster
patent: 5346905 (1994-09-01), Gerster
patent: 5352784 (1994-10-01), Nikolaides et al.
patent: 5367076 (1994-11-01), Gerster
patent: 5389640 (1995-02-01), Gerster et al.
patent: 5395937 (1995-03-01), Nikolaides et al.
patent: 5446153 (1995-08-01), Lindstrom et al.
patent: 5482936 (1996-01-01), Lindstrom
patent: 5693811 (1997-12-01), Lindstrom
patent: 5741908 (1998-04-01), Gerster et al.
patent: 5756747 (1998-05-01), Gerster et al.
patent: 5939090 (1999-08-01), Beaurline et al.
patent: 6039969 (2000-03-01), Tomai et al.
patent: 6069149 (2000-05-01), Nanba et al.
patent: 6083505 (2000-07-01), Miller et al.
patent: 6110929 (2000-08-01), Gerster et al.
patent: 6194425 (2001-02-01), Gerster et al.
patent: 6245776 (2001-06-01), Skwierczynski et al.
patent: 6331539 (2001-12-01), Crooks et al.
patent: 6376669 (2002-04-01), Rice et al.
patent: 6451810 (2002-09-01), Coleman et al.
patent: 6486168 (2002-11-01), Skwierczynski et al.
patent: 6518265 (2003-02-01), Kato et al.
patent: 6525064 (2003-02-01), Dellaria et al.
patent: 6541485 (2003-04-01), Crooks et al.
patent: 6545016 (2003-04-01), Dellaria et al.
patent: 6545017 (2003-04-01), Dellaria et al.
patent: 6558951 (2003-05-01), Tomai et al.
patent: 6573273 (2003-06-01), Crooks et al.
patent: 6656938 (2003-12-01), Crooks et al.
patent: 6660735 (2003-12-01), Crooks et al.
patent: 6660747 (2003-12-01), Crooks et al.
patent: 6664260 (2003-12-01), Charles et al.
patent: 6664264 (2003-12-01), Dellaria et al.
patent: 6664265 (2003-12-01), Crooks et al.
patent: 6667312 (2003-12-01), Bonk et al.
patent: 6670372 (2003-12-01), Charles et al.
patent: 6677347 (2004-01-01), Crooks et al.
patent: 6677348 (2004-01-01), Heppner et al.
patent: 6677349 (2004-01-01), Griesgraber
patent: 6683088 (2004-01-01), Crooks et al.
patent: 6706728 (2004-03-01), Hedenstrom et al.
patent: 6743920 (2004-06-01), Lindstrom et al.
patent: 6756382 (2004-06-01), Coleman et al.
patent: 6780873 (2004-08-01), Crooks et al.
patent: 6784188 (2004-08-01), Crooks et al.
patent: 6797718 (2004-09-01), Dellaria et al.
patent: 6818650 (2004-11-01), Griesgraber
patent: 6825350 (2004-11-01), Crooks et al.
patent: 6855217 (2005-02-01), Suzuki
patent: 6894060 (2005-05-01), Slade
patent: 6897221 (2005-05-01), Crooks et al.
patent: 6924293 (2005-08-01), Lindstrom
patent: 2002/0016332 (2002-02-01), Slade
patent: 2002/0055517 (2002-05-01), Smith
patent: 2002/0058674 (2002-05-01), Hedenstrom et al.
patent: 2002/0110840 (2002-08-01), Tomai et al.
patent: 2003/0130299 (2003-07-01), Crooks et al.
patent: 2003/0133913 (2003-07-01), Tomai et al.
patent: 2003/0139364 (2003-07-01), Krieg et al.
patent: 2003/0161797 (2003-08-01), Miller et al.
patent: 2003/0199538 (2003-10-01), Skwierczynski et al.
patent: 2004/0014779 (2004-01-01), Gorden et al.
patent: 2004/0091491 (2004-05-01), Kedl et al.
patent: 2004/0132079 (2004-07-01), Gupta et al.
patent: 2004/0141950 (2004-07-01), Noelle et al.
patent: 2004/0147543 (2004-07-01), Hays et al.
patent: 2004/0162309 (2004-08-01), Gorden et al.
patent: 2004/0171086 (2004-09-01), Fink et al.
patent: 2004/0175336 (2004-09-01), Egging et al.
patent: 2004/0176367 (2004-09-01), Griesgraber et al.
patent: 2004/0180919 (2004-09-01), Lee et al.
patent: 2004/0181130 (2004-09-01), Fox et al.
patent: 2004/0181211 (2004-09-01), Elliott et al.
patent: 2004/0191833 (2004-09-01), Fink et al.
patent: 2004/0192585 (2004-09-01), Fox et al.
patent: 2004/0197865 (2004-10-01), Gupta et al.
patent: 2004/0202720 (2004-10-01), Wightman et al.
patent: 2004/0214851 (2004-10-01), Birmachu et al.
patent: 0 394 026 (1990-10-01), None
patent: 1 104 764 (2001-06-01), None
patent: 210 051 (1995-01-01), None
patent: 218 950 (2001-01-01), None
patent: 9-208584 (1997-08-01), None
patent: 9-255926 (1999-03-01), None
patent: 11-222432 (1999-08-01), None
patent: 2000-247884 (ABS) (2000-09-01), None
patent: WO 00/76519 (2000-12-01), None
patent: WO 01/74343 (2001-10-01), None
patent: WO 02/36592 (2002-05-01), None
patent: WO 02/46749 (2002-06-01), None
patent: WO 02/102377 (2002-12-01), None
patent: WO 03/020889 (2003-03-01), None
patent: WO 03/043572 (2003-05-01), None
patent: WO 03/045391 (2003-06-01), None
patent: WO 03/097641 (2003-11-01), None
patent: WO 04/091500 (2004-10-01), None
Cecil Textbook of Medicine, 21stEdition, vol. 1, published 2000 by W.B. Saunders Company (PA), pp. 1060-1074.
Drug Actions, Basic Principles and Therapeutic Aspects, published 1995 by CRC Press (Boca Raton), pp. 515-580.
Wozniak, et al, “The Amination of 3-nitro-1, 5-naphthyridines by Liquid Ammonia/Potassium Permanganate1,2. A New and Convenient Amination Method.”,Journal of the Royal Netherlands Chemical Society, 102, pp. 511-513, Dec. 12, 1983.
Brennan, et al, “Automated Bioassay of Interferrons in Micro-test Plates”,Biotechniques, Jun./Jul., 78, 1983.
Testerman, et al., “Cytokine Induction by the Immunomodulators Imiquimod and S-27609”,Journal of Leukocyte Biology, vol. 58, pp. 365-372, Sep. 1995.
Bachman, et al, “Synthesis of Substituted Quinolylamines. Derivatives of 4-Amino-7-Chloroquinoline”,J. Org. Chem, 15, pp. 1278-1284 (1950).
Jain, et al, “Chemical and Pharmacological Investigations of Some ω-Substituted Alkylamino-3-aminopyridines”,J. Med. Chem., 11, pp. 87-92 (1968).
Baranov, et al.,Chem. Abs. 85, 94362, (1976).
Berényi, et al, “Ring Transformation of Condensed Dihydro-as-triazines”,J. Heterocyclic Chem., 18, pp. 1537-1540 (1981).
Chollet, et al, “Development of a Topically Active Imiquimod Formulation”,Pharmaceutical Development and Technology, 4(1), pp. 35-43 (1999).
Izumi, et al., “1H-Imidazo[4,5-c]quinoline Derivatives as Novel Potent TNF-α Suppressors: Synthesis and Structure-Activity Relationship of 1-, 2- and 4-Substituted 1H-imidazo[4,5-c]pyridines”,Bioorganic&Medicinal Chemistry, 11, pp. 2541-2550 (2003).
Cohen et al., American Journal of Clinical Pathology, 105(5), pp. 589-598 (1996).
Rollins BJ, Blood, 90(3), pp. 909-928 (1997).
Bernstein et al., “Daily or Weekly Therapy with Resiquimod (R-848) Reduces Genital Recurrences in Herpes Simplex Virus-Infected Guinea Pigs during and after Treatment”,J of Infectious Diseases, vol. 183(6), pp. 844-849, 2001.
Diaz-Arrastia et al., “Clinical and Molecular Responses in High-Grade Intraepithelial Neoplasia Treated with Topical Imiquimod 5%”,Clinical Cancer Research, vol. 7(10), pp. 3031-3033, 2001.
Spruance et al., “Application of a Topical Immune Response Modifier, Resiquimod Gel, to Modify the Recurrence Rate of Recurrent Genital Herpes: A Pilot Study”,J of Infectious Diseases, vol. 184(2), pp. 196-200, 2001.
3M Innovative Properties Company
Ersfeld Dean A.
Henley III Raymond J.
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