Versican and epithelial-mesenchymal interaction

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus

Reexamination Certificate

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C435S325000, C800S008000

Reexamination Certificate

active

09565949

ABSTRACT:
The invention describes versican activation and modulation of hair growth, e.g., versican expressing dermal papilla cells exhibit hair induction ability.

REFERENCES:
patent: 5180808 (1993-01-01), Ruoslahti
patent: 5908867 (1999-06-01), Henry et al.
patent: 6689936 (2004-02-01), Burgeson et al.
patent: 633 315 (1995-01-01), None
patent: WO 96 37237 (1996-11-01), None
patent: WO 99/30743 (1999-06-01), None
GenBank Accession No. NT 00654, 2002.
GenBank Accession No. UI 5963, 2002.
Ebert et al.; A Moloney MLV-Rat Somatotropin Fusion Gene Produces Biologically Active Somatotropin in a Transgenic Pig, 1988, Molecular Endocrinology 2: 277-283.
Mullins et al.; Perspectives Series: Molecular Medicine in Genetically Engineered Animals, 1996, J. Clin. Invest.: 1557-1560.
Wall et. al.; Transgenic Dairy Cattle: Genetic Engineering on a Large Scale , 1997, J Dairy Sci. 80: 2213-2224.
Hammer et.al.; Genetic Engineering Of Mammalian Embryos, 1986, J. Anim. sci. 63: 269-278.
Moreadith et al.; Gene targeting in embryonic stem cells: the new physiology and metabolism, 1997, J. Moi. Med. 75: 208-216.
Seamark; Progress and Emerging Problems in Livestock Transgenesis: a Summary Perspective, 1994, Reprod. Fertil. Dev. 6: 653-657.
Chalfie et al., “Green Fluorescent Protein as a Marker for Gene Expression”, Science, vol. 26, Feb. 11, 1994:802-805.
Kishimoto et al., “Human Versican Promoter-Driven Lacz . . . ”, J. Investigative Dermatology, vol. 110, No. 4, Apr. 1998:151.
Kishimoto et al., “Versican Promoter Transactivation in Dermal Papilla . . . ”, J. Investigative Dermatology, vol. 112, No. 4, Apr. 1999:678.
Kishimoto et al., “Selective activation of the versican . . . ”, Proc. Natl. Acad. Sci. USA, vol. 96, Jun. 1999:7336-7341.
Kishimoto et al., “Developmental Study of Human Versican . . . ”, Glycosaminoglycans and Proteoglycans, vol. 8, No. Supplement, p. 394A; 2292.
Naso et al., “Characterization of the Complete Genomic Structure of the Human . . . ”, J. Biological Chemistry, vol. 269, No. 52, Dec. 30, 1994:32999-33008.
Zimmermann et al., “Versican Is Expressed in the Proliferating Zone . . . ”, J. Cell Biology, vol. 124, No. 5, Mar. 1994:817-825.
Du Cros et al., “Association of Versican with Dermal Matrices . . . ”, 1995, J.Invest. Derm. 105(3);426-431.
Kishimoto et al., “Human Versican Promoter-Driven Lacz Activity . . . ”, 1998, J. Derm. Sci. 16(suppl. 1);S26.
Rhode et al., “The retinoblastoma protein modulates expression . . . ”, 1996, Oncogene 12(11);2393-2401.
Cachon-Gonzalez et al. “Structure and Expression of the Hairless Gene of Mice”, Proc. Natl. Acad. Sci., USA, vol. 91, pp. 7717-7721 (1994).
Mohan J. Investigative Dermatology, vol. 106, p. 906, abstract 605, 1996.
Davis et al.,A Nuclear GFP That Marks Nuclei in Living Drosophila Embroys; Maternal Supply Overcomes a Delay in the Appearance of Zygotic Fluorescence, Develop. Biol., 170:726-729 (1995).
Mullins,Molecular Medicine in Genetically Engineered Animals, J. Clin. Invest., vol. 98, pp. S37-S40), 1996.
Mullins et al.,Expression of the DBA/2J ren-2 gene in the adrenal gland of transgemic mice, 1989, The EMBO Journal, vol. 8, pp. 4065,4072.
Mullins et al.,Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene, 1990, Nature, vol. 344, pp. 541-544.
Hammer et al.,Spontaneous inflammatory disease in transgemic rats expressing HLA-B27 and Human B2m: An animal model of HLA-B27-associtaed human disorders, 1990, Cell, vol. 63, pp. 1099-1112.
Taurog et al.,HLA-B27 in inbred and non-inbred transgenic mice: Cell surface expression and recognition as an alloantigen in the absence of human B2-microglobulin, 1988, The Journal of Immunology, vol. 141, pp. 4020-4023.
Okabe et al., ‘Green mice’ as a source of ubiquitous green cells, 1997, FERS Letters, vol. 407, pp. 313-319.
Gille Jens et al, “Transforming growth factor—alpha—induced transcriptional activation of the vascular permeability factor(VPF/FEGF)gene requires AP-2-dependent DNA binding and transactivation”, EMBO (European Molecular Biology Organization) Journal, vol. 16, No. 4, 1997, pp. 750-759, XP002164519.
Ramirez, A. et al., “A 5′-upstream region of a bovine keratin 6 gene confers tissue-specific expression and hyperproliferation-related induction in transgenic mice,” Proceedings of the National Academy of Sciences of the United States of America, vol. 92, May 1995, pp. 4783-4787, XP002156382.
Bernstein, E.F. et al., “Evaluation of sunscreens with various sun protection factors in a new transgenic mouse model of cutaneous photoaging that measure elastin promoter activation”, Journal of the American Academy of Dermatology, US, C.V. Mosby, St. Louis, MO, vol. 37, No. 5, Part 01, Nov. 1997, pp. 725-729, XP002117296.
Ikawa, M. et al., “Green fluorescent protein as a marker in transgenic mice” Development of growth and differentiation, JP, Japanese Society of Developmental Biologists, vol. 37, Aug. 1, 1995, pp. 455-459, XP002086829.
Damak et al. “Expression of Human Neutrophil Elastase Gene in the Lungs of Transgenic Mice”, J. Cellular & Biochemistry Supp., Abstract V102; Apr. 3, 1992.
Himelstein et al., Oncogene 14(16): 1995-1998 (1997).
Kemp et al. “The Glycosylation of Alpha-1 Antitrypsin in Transgenic Mice”, Animal Cell Technology: Basic: Applied Aspects, 8th Annual Conference, edited by Funatsu et al., the Netherlands: Kluwer Academic Publishers 8:517-522 (1997).
Rice et al.,Detection of Gelatinase B Expression Reveals Osteoclastic Bone Resorpotion as a Feature of Early Calvarial Bone Development, Bone, 21(6):479-486 (Dec. 1997).
Simon et al.,Suppressor and Activator Functions Mediated by a Repeated Heptad Sequence in the Liver Fatty Acid-binding Protein Gene(Fabpl), J. of Biological Chemistry, 272(16):10651-10663 (Apr. 18, 1997).
Yoshizaki et al.,Increased Expression of Membrane Type 1-Matrix Metalloproteinase in Head and Neck Carcinoma, Cancer, 79(1):139-144.
Zhang et al.,An Enhanced Green Fluorescent Protein Allows Sensitive Detection of Gene Transfer in Mammalian Cells, Biochem. Biophys. Res. Commun., 227:707-711 (1996).
Mistelli & Spector,Applications of the green fluorescent protein in cell biology and biotechnology, Nat. Biotechnol., 15:961-964 (1997).
Chiocchetti et al.,Green fluorescent protein as a reporter of gene expression in transgenic mice, Biochem. Biophys. Act., 1352:193-202 (1997).
Zhuo et al.,Live Astrocytes Visualized by Green Fluorescent Protein in Transgenic Mice, Dev. Biology, 187:36-42 (1997).
Detmar et al.,Molecular Regulation of Angiogenesis in the Skin, J. Invest. Dermatol., 106:207-208 (1996).
Brown, et al.,Expression of Vascular Permeability Factor(Vascular Endothelial Growth Factor)by Epidermal Keratinocytes during Wound Healing, J. Exp. Med., 176:1375-1379 (1992).
Larcher et al.,Up-Regulation of Vascular Endothelial Growth Factor/Vascular Permeability Factor in Mouse Skin Carcinogenesis Correlates with Malignant Progression State and Activated H-ras Expression Levels, Cancer Res., 56:5391-5396 (1996).
Bernstein et al.,Differential Expression of the Versican and Decorin Genes in Photaged and Sun-Protected Skin, Laboratory Investigation, 72:662-669 (1995).
Huhtala et al.,Complete Structure of the Human Gene for 92-kDa Type IV Collagenase, The Journal of Biological Chemistry, 266:16485-16490 (1991).
Itano et al.,Molecular Cloning of Human Hyaluronan Synthase, Biochemical and Biophysical Research Communications, 222:816-820 (1996).
Mauch et al.,Role of the extracellular matrix in the degradation of connective tissue, Arch. Dermatol. Res., 287:107-114 (1994).
Spicer et al.,Molecular Cloning and Characterization of a cDNA Encoding the Third Putative Mammalian Hyaluronan Synthase, The Journal of Bioligical Chemistry, 272:8957-8961 (1997).
Takahashi et al.,Structure of the Human Neutrophil Elastase Gene, The Journal of Biological Chemistry, 263:14739-14747 (1988).
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