Tissue plasminogen activator-like protease

Details Tissue plasminogen activator-like protease Tissue plasminogen activator-like protease

2007-04-17

2007-04-17

Slobodyansky, Elizabeth (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

C435S217000, C435S252300, C435S320100, C435S325000, C435S455000, C536S023200, C536S023400, C536S023500

Reexamination Certificate

active

10894043

ABSTRACT:
The present invention relates to a novel t-PALP protein which is a member of the serine protease family. In particular, isolated nucleic acid molecules are provided encoding the human t-PALP protein. t-PALP polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of t-PALP activity. Also provided are diagnostic methods for detecting circulatory system-related disorders and therapeutic methods for treating circulatory system-related disorders.

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