Glycopeptide phosphonate derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C514S008100, C530S317000, C530S322000

Reexamination Certificate

active

11265570

ABSTRACT:
Disclosed are glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups; and pharmaceutical compositions containing such glycopeptide derivatives. The disclosed glycopeptide derivatives are useful as antibacterial agents.

REFERENCES:
patent: 4643987 (1987-02-01), Nagarajan et al.
patent: 4698327 (1987-10-01), Nagarajan et al.
patent: 4727064 (1988-02-01), Pitha
patent: 4983586 (1991-01-01), Bodor
patent: 5024998 (1991-06-01), Bodor
patent: 5217493 (1993-06-01), Raad et al.
patent: 5591714 (1997-01-01), Nagarajan et al.
patent: 5602112 (1997-02-01), Rubinfeld
patent: 5750509 (1998-05-01), Malabarba et al.
patent: 5840684 (1998-11-01), Cooper et al.
patent: 5916873 (1999-06-01), Cooper et al.
patent: 6111084 (2000-08-01), Wong et al.
patent: 6323176 (2001-11-01), Jamison et al.
patent: 6392012 (2002-05-01), Judice et al.
patent: 6635618 (2003-10-01), Leadbetter et al.
patent: 6872701 (2005-03-01), Leadbetter et al.
patent: 6887976 (2005-05-01), Leadbetter et al.
patent: 6979723 (2005-12-01), Leadbetter et al.
patent: 7008923 (2006-03-01), Leadbetter et al.
patent: 7015307 (2006-03-01), Schmidt et al.
patent: 7074890 (2006-07-01), Leadbetter et al.
patent: 2005/0164916 (2005-07-01), Leadbetter et al.
patent: 0 667 353 (1995-08-01), None
patent: 0 816 378 (1998-01-01), None
patent: 2000-302687 (2000-10-01), None
patent: WO 94/12217 (1994-06-01), None
patent: WO 00/04044 (2000-01-01), None
patent: WO 00/39156 (2000-07-01), None
patent: WO 00/54751 (2000-09-01), None
patent: WO 00/59528 (2000-10-01), None
patent: WO 01/82971 (2001-11-01), None
patent: WO 01/83520 (2001-11-01), None
patent: WO 01/97851 (2001-12-01), None
patent: WO 01/98326 (2001-12-01), None
patent: WO 01/98327 (2001-12-01), None
patent: WO 01/98329 (2001-12-01), None
Allen et al., “The Role of Hydrophobic Side Chains as Determinants of Antibacterial Activity of Semisynthetic Glycopeptide Antibiotics”, The Journal of Antibiotics, vol. 50, No. 8, pp. 677-684 (1997).
GE et al., “Vancomycin Derivatives That Inhibit Peptidoglycan Biosynthesis Without Binding D-Ala-D-Ala”, Science, vol. 284, pp. 507-511 (1999).
Malabarba et al., “New Semisynthetic Glycopeptides MDL 63,246 and MDL 63,042, and Other Amide Derivatives of Antibiotic A-40, 926 Active against Highly Glycopeptide-resistant VanA Enterococci”, The Journal of Antibiotics, vol. 48, No. 8, pp. 869-883 (1995).
Nagarajan et al., “Synthesis and Antibacterial Evaluation ofN-Alkyl Vancomycins”, The Journal of Antibiotics, vol. XLII, No. 1, pp. 63-72 (1989).
Nicolaou et al., “Chemistry, Biology and Medicine of the Glycopeptide Antibiotics”, Angew. Chem. Int. Ed., vol. 38, pp. 2097-2152 (1999).
Pavlov et al., “A New Type of Chemical Modification of Glycopeptides Antibiotics: Aminomethylated Derivatives of Eremomycin and Their Antibacterial Activity”, The Journal of Antibiotics, vol. 50, No. 6, pp. 509-513 (1997).
Pavlov et al., “Chemical Modification of Glycopeptide Antibiotics [VC1]”, Russian Journal of Bioorganic Chemistry, vol. 24, No. 9, pp. 570-587 (1998).
Pavlov et al., “Mono and Double Modified Teicoplanin Aglycon Derivatives on the Amino Acid No. 7; Structure-activity Relationship”, The Journal of Antibiotics, vol. 51, No. 1, pp. 73-78 (1998).
Zhang et al., “A review of recent applications of cyclodextrins for drug discovery”, Expert Opinion on Therapeutic Patents, vol. 9, No. 12, 21 pages (1999).
deBree et al., “Structure-Function Relationships of the Vasopressin Prohormone Domains”, Cellular and Molecular Neurobiology, vol. 18, No. 2, pp. 173-191 (1998).
Sears et al., “Intervention of carbohydrate recognition by proteins and nucleic acids”, Proc. Natl. Acad. Sci. USA, vol. 93, pp. 12086-12093 (Oct. 1996).
Lampe et al., “Parallel Synthesi of Sialyl Lewis X Mimetics on a Solid Phase: Access to a Library of Fucopeptides”, Angew. Chem. Int. Ed., vol. 37, No. 12, pp. 1707-1711 (1998).

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