Methods and pharmaceutical formulations for the treatment of...

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...

Reexamination Certificate

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C424S133100, C424S141100, C424S145100

Reexamination Certificate

active

10274788

ABSTRACT:
A method of treating pulmonary hypertension in a subject in need of such treatment comprises inhibiting EMAP II activity in the subject by an amount effective to treat the pulmonary hypertension in the subject (e.g., in the lungs and more particularly in the pulmonary vasculature). Pharmaceutical formulations useful for carrying out such methods (e.g., an antibody that specifically binds to EMAP II in a pharmaceutically acceptable carrier) and screening techniques useful for identifying additional compounds that can be used for carrying out such methods are also disclosed.

REFERENCES:
patent: 5641867 (1997-06-01), Stern et al.
patent: WO95/09180 (1995-04-01), None
patent: WO 00/29620 (2000-05-01), None
patent: WO 01/47518 (2001-07-01), None
Stryer et al, in Biochemistry, Third edition, W H Freeman Company, New York, pp. 31-33, 1998.
Gallie et al, Eur Respir J 20: 1037-149, 2002.
Abstract, Schwarz, Margaret, et al., Emap ii: a modulator of neovascularization in the developing lung,APStracts 5:0339L(1998).
Gaine, Sean P., et al., Primary pulmonary hypertension,Lancet, vol. 352, pp. 719-725 (1998).
Bennett et al.,Biochemical Pharmacology, vol. 55, pp. 9-19 (1998).
Kao, Janet, et al.; Characterization of a Novel Tumor-derived Cytokine,The Journal of Biological Chemistry, vol. 269, No. 40, pp. 25106-25119 (Oct. 7, 1994).

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