Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2007-07-10
2007-07-10
Bragdon, Kathleen Kerr (Department: 1656)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Reexamination Certificate
active
10960642
ABSTRACT:
Provided are crystals relating to human Glucocorticoid Receptor and its various uses.
REFERENCES:
Creighton. T., “Encyclopedia of Molecular Biology”, John Wiley and Sons, Inc. New York, 1999, pp. 586 and 2725.
Weber, P.C. Overview of Crystallization Methods. Methods in Enzymology, 1997, vol. 276, pp. 13-22.
Drenth, J. “Principles of Protein X-Ray Crystallography”, 2nd Edition, 1999 Springer-Verlag New York Inc., Chapter 1, pp. 1-19.
Cudney, R. Protein Crystallization and Dumb Luck. Rigaku Journal. 1999. vol. 16, No. 1, pp. 1-7.
Bledsoe et al. Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition. Cell. Jul. 2002. vol. 110, pp. 93-105.
Sequence alignment of Bledsoe et al. crystal sturcture sequence from pdb file 1M2Z and SEQ ID No. 1 528-777.
Brodsky Oleg
Brooun Alexei
Chien Ellen
Dougan Douglas R.
Mol Clifford D.
Bragdon Kathleen Kerr
Noakes Suzanne M.
Takeda San Diego, Inc.
Weitz David J.
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