Acyloxypyrrolidine derivatives, preparation thereof and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S466000

Reexamination Certificate

active

11038384

ABSTRACT:
The invention relates to acyloxypyrrolidine derivatives of general formula (I):in which:R1represents a hydrogen atom, a (C1–C6)alkyl, a (C3–C6)cycloalkyl, a group —CH2CH2COOH or a group —NR2R3;R2and R3each represent, independently, a hydrogen atom or a (C1–C6)alkyl. Also disclosed and claimed are the method of preparation of the compounds of the invention and their application in therapeutics.

REFERENCES:
patent: WO 01/55130 (2001-08-01), None
Cancer and Metastasis Reviews (1998), 17(1), 91-106.
Science (1999), vol. 286, 531-537.
Akerlund, Prog. Brain Res. vo. 139, p. 359-65 (2002) (abstract).
Paranjape et al. Expert Opinion on Investigational Drugs, vol. 10(5), p825-834 (2001).

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