Method of treating reproductive system cancer by...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S008100, C514S012200, C530S350000

Reexamination Certificate

active

11155114

ABSTRACT:
The present invention relates to a novel follistatin-3 protein which is a member of the family of inhibin-related proteins. In particular, isolated nucleic acid molecules are provided encoding the human follistatin-3 protein. Follistatin-3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of follistatin-3 activity. Also provided are diagnostic methods for detecting reproductive system-related disorders and disorders of the regulation of cell growth and differentiation and therapeutic methods for treating reproductive system-related disorders and disorders of the regulation of cell growth and differentiation.

REFERENCES:
patent: 5942420 (1999-08-01), Holtzman
patent: WO-99/55865 (1999-04-01), None
patent: WO-99/25371 (1999-05-01), None
patent: WO-99/31237 (1999-06-01), None
Beers and Berkow (1999). The Merck Manual of Diagnosis and Therapy. 17thedition, pp. 986-995.
Genbank Accession No. N52331, Hillier et al., (Jan. 30, 1997), Genome Res., 6(9):807-828 (1996).
Genbank Accession No. AA552990, National Cancer Insitute, Cancer Genome Anatomy Project (Aug. 11, 1997).
Genbank Accession No. N28854, Hillier et al., The WashU-Merck EST Project (Jan. 4, 1996).
Genbank Accession No. R74502, Hillier et al., The WashU-Merck EST Project (Jun. 5, 1995).
Genbank Accession No. N75101, Hillier et al., (Jan. 30, 1997), Genome Res., 6(9):807-828 (1996).
Genbank Accession No. AC004156, Lamerdin et al., Sequence analysis of a 3.5 Mb contig in human 19p13.3 containing a serine protease gene cluster (Feb. 19, 1998).
Genbank Accession No. AA375541, Adams et al., (Apr. 21, 1997), Nature 377(6547 Suppl):3-174 (1995).
Genbank Accession No. AA363365, Adams et al., (Apr. 21, 1997), Nature Genet., 4:373-380 (1993).
Genbank Accession No. AC004156 Lamerdin et al., “Homo sapienschromosome 19, cosmid R33586.” (Feb. 19, 1998).
Genbank Accession No. AA227791, Hillier et al., Wash U.—Merck EST Project (Aug. 6, 1997).
Genbank Accession No. N32892, Hillier et al., Wash. U.—Merck EST Project (Jan. 10, 1996).
Genbank Accession No. AA470722, National Cancer Institute, Cancer Genome Anatomy Project (Aug. 14, 1997).
Genbank Accession No. AA492556, National Cancer Institute, Cancer Genome Anatomy Project (Aug. 19, 1997).
Genbank Accession No. N42037, Hillier et al., Wash. U.-Merck EST Project (Jan. 24, 1996).
U.S. Appl. No. 09/912,292, Rosen et al.
Genbank Accession No. R72628, Hillier et al., Wash. U.-Merck EST Project (Jun. 2, 1995).
Genbank Accession No. H42225, Hillier et al., Wash. U.-Merck EST Project (Jul. 31, 1995).
Genbank Accession No. H24937, Hillier et al., Wash. U.-Merck EST Project (Jul. 7, 1995).
Genbank Accession No. R79389, Hillier et al., Wash. U-Merck EST Project (Jun. 9, 1995).
Genbank Accession No. H43043, Hillier et al., Wash. U-Merck EST Project (Jul. 31, 1995).
Genbank Accession No. AA227956, Hillier et al., Wash. U-Merck EST Project (Aug. 6, 1997).
Genbank Accession No. H14559, Hillier et al., Wash. U-Merck EST Project (Jun. 27, 1995).
Genbank Accession No. AA470654, National Cancer Institute, Cancer Genome Anatomy Project ( Aug. 14, 1997).
Genbank Accession No. H42566, Hillier et al., Wash. U.-Merck EST Project (Jul. 31, 1995).
Genbank Accession No. R79390, Hillier et al., Wash. U.-Merck EST Project (Jun. 9, 1995).
Genbank Accession No. R72699, Hillier et al., Wash. U.-Merck EST Project (Jun. 2, 1995).
Genbank Accession No. AA258582, Hillier et al., Wash. U.-Merck EST Project (Aug. 6, 1997).
Genbank Accession No. AA365825 (Apr. 21, 1997), Adams et al., Nature, 377(6547 Suppl.):3-174 (1995).
Genbank Accession No. AA020306, Marra et al., Wash. U-HHMI mouse EST Project (Jan. 21, 1997).
Genbank Accession No. H51168, Hillier et al., Wash. U.-Merck EST Project (Sep. 18, 1995).
Genbank Accession No. R46195, Hillier et al., Wash. U.-Merck EST Project (May 10, 1995).
Genbank Accession No. AA015105, Marra et al., Wash. U-HHMI mouse EST Project (Jan. 21, 1997).
Genbank Accession No. W18317, Marra et al., Wash. U-HHMI mouse EST Project (Sep. 10, 1996).
Genbank Accession No. D31566 (Feb. 8, 1995), Sudo et al., Genomics, 24:276-279 (1995).
Genbank Accession No. W14649, Marra et al., Wash U-HHMI mouse EST Project (Sep. 10, 1996).
Genbank Accession No. AA568792, National Cancer Institute Cancer Genome Anatomy Project (Aug. 22, 1997).
Hayette et al., Oncogene, 16:2949-2954 (1998).
Shimasaki et al., PNAS, 85:4218-4222 (1988).
Genbank Accession No. AA421552, Hillier et al. “Homo sapienscDNA clone” (May 19, 1997).
European Search Report, Application No. EP 98 94 1072.5, dated Jul. 25, 2000.
International Search Report, Application No. PCT/US00/19198, dated Nov. 14, 2000.
Mikayama et al., Proc. Natl. Acad. Sci. USA, 90:10056-10060 (1993).
Voet et al., Biochemistry, John Wiley & Sons, Inc., pp. 126-128 and 228-234 (1990).
Hemmati-Brivanlou, et al., Cell, 77:283-295 (1994).
Genbank Accession No. AA470722, National Cancer Institute, “Homo sapienscDNA clone” (Jun. 21, 1997).
Genbank Accession No. AA227791, Hillier et al., “Homo sapienscDNA clone” (Feb. 27, 1997).
Sugino et al., J Med Invest. 44(1-2):1-14 (Aug. 1997); Abstract only.
Hashimoto et al., J Biol Chem. 272(21):13835-42 (May 23, 1997).
Di Simone et al., Endocrinology 137:486-494 (1996).
Bartholin et al., Oncogene 21:2227-2235 (2002); Abstract only.
Ciarmela et al., Eur J Endocrinol 151:251-257 (2004).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of treating reproductive system cancer by... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of treating reproductive system cancer by..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of treating reproductive system cancer by... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3778390

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.