Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Reexamination Certificate
2007-01-30
2007-01-30
Carr, Deborah D. (Department: 1621)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
C554S066000, C554S040000, C554S041000, C564S353000, C564S503000
Reexamination Certificate
active
10398305
ABSTRACT:
The present invention is directed to compositions comprising lysophosphatidic acid analogs and methods of using such analogs as agonist or antagonists of LPA receptor activity. In addition the invention is directed to LPA receptor agonists that vary in the degree of selectivity at individual LPA receptors (i.e. LPA1, LPA2 and LPA3). More particularly the present invention is directed to LPA analogs wherein the glycerol is replaced with ethanolamine and a variety of substitutions have been linked at the second carbon atom.
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Heise Christopher E.
Lynch Kevin R.
Macdonald Timothy L.
Okusa Mark D.
Santos Webster L.
Carr Deborah D.
Sparks Rodney L.
University of Virginia Patent Foundation
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