Anti-cancer composition for delivering 5-fluorouracil

Details Anti-cancer composition for delivering 5-fluorouracil Anti-cancer composition for delivering 5-fluorouracil

1984-03-20

1986-11-11

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

424 10, A61K 31505

Patent

active

046223258

ABSTRACT:
An anti-cancer composition for delivering 5-fluorouracil to cancer tissues in a warm-blooded animal, wherein the cancer is a cancer sensitive to 5-fluorouracil, comprising 1-n-hexylcarbamoyl-5-fluorouracil and uracil (or salt there-of), wherein the composition contains less than 0.1 mole of the 5-fluorouracil per mole of the uracil.

REFERENCES:
patent: 4481203 (1984-11-01), Fujii et al.
Burchewal et al., Cancer Chemotherapy Repts., 6, pp. 1-5 (1960).
Chemical Abstracts 86:50590p (1976).
Jato et al., J. of Pharm. Sciences 62, pp. 1975-1978, (Dec. 1978).
Jato et al., J. of Pham. Sciences 64, pp. 943-946 (Jun. 1975).

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