Surgery – Respiratory method or device – Means for mixing treating agent with respiratory gas
Patent
1994-09-27
1996-06-04
Funk, Stephen
Surgery
Respiratory method or device
Means for mixing treating agent with respiratory gas
12820014, 12820019, 12820417, 12820312, A61M 1600
Patent
active
055223850
ABSTRACT:
A device is provided which creates aerosolized particles by forcing a formulation of drug in a carrier through a nozzle (which nozzle may be in the form of a porous membrane) into a channel to a patient for inhalation. While in the channel energy is added to the particles in an amount sufficient to evaporate carrier and thereby reduce particle size. The amount of energy added can be adjusted depending on factors such as the particle size, the amount of the carrier to be evaporated, the water vapor content of the surrounding air and the composition of the carrier. Energy may be added in an amount sufficient to evaporate all carrier and thereby provide particles of dry powdered drug to patient which particles are uniform in size regardless of the surrounding humidity and smaller due to the evaporation of the carrier. Air drawn into the device by the patient may be drawn through a desiccator containing a desiccant which removes moisture from the air thereby improving evaporation efficiency when the carrier is water. Alternatively, water vapor may be introduced to the channel to saturate inhaled air thereby preventing evaporation of carrier and maintaining uniform particle size.
REFERENCES:
patent: 3157179 (1964-11-01), Paullus et al.
patent: 3187748 (1965-06-01), Mitchell et al.
patent: 3456646 (1969-07-01), Phillips et al.
patent: 3565070 (1971-02-01), Hanson et al.
patent: 3812854 (1974-05-01), Michaels et al.
patent: 3826413 (1974-07-01), Warren
patent: 3861386 (1975-01-01), Harris et al.
patent: 3948264 (1976-04-01), Wilke et al.
patent: 3991304 (1976-11-01), Hillsman
patent: 4256017 (1981-03-01), Eastman
patent: 4274403 (1981-06-01), Struve
patent: 4524769 (1985-06-01), Wetterlin
patent: 4533082 (1985-08-01), Maehara et al.
patent: 4564748 (1986-01-01), Gupton
patent: 4627432 (1986-12-01), Newell et al.
patent: 4649911 (1987-03-01), Knight et al.
patent: 4699136 (1987-10-01), Krauser
patent: 4832012 (1989-05-01), Raabe et al.
patent: 4877989 (1989-10-01), Drews et al.
patent: 4922901 (1990-05-01), Brooks et al.
patent: 4963327 (1990-10-01), Russell
patent: 5042472 (1991-08-01), Bunin
patent: 5063921 (1991-11-01), Howe
patent: 5152456 (1992-10-01), Ross et al.
patent: 5156776 (1992-10-01), Loedding et al.
patent: 5186164 (1993-02-01), Raghuprasad
patent: 5201308 (1993-04-01), Newhouse
patent: 5327883 (1994-07-01), Williams et al.
patent: 5372148 (1994-12-01), McCafferty
patent: 5383850 (1995-01-01), Schwab et al.
patent: 5396884 (1995-03-01), Bagwell et al.
patent: 5404871 (1995-04-01), Goodman et al.
Newman, Stephen P., "Deposition and Effects of Inhalation Aerosols," Rahms i Lund Tryckeri AB, 1983, pp. 1-113.
Lloyd Lester J.
Lloyd Peter M.
Rubsamen Reid M.
Schuster Jeffrey A.
Aradigm Corporation
Bozicevic Karl
Funk Stephen
Raciti Eric P.
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