Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Reexamination Certificate
2007-01-09
2007-01-09
Padmanabhan, Sreeni (Department: 1617)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
C424S070100, C424S424000, C514S572000
Reexamination Certificate
active
10636466
ABSTRACT:
Mammalian hair growth can be reduced by topical application of an inhibitor of fatty acid metabolism.
REFERENCES:
patent: 3426137 (1969-02-01), Philpitt et al.
patent: 4039669 (1977-08-01), Beyler et al.
patent: 4139638 (1979-02-01), Neri et al.
patent: 4161540 (1979-07-01), Neri et al.
patent: 4191775 (1980-03-01), Glen
patent: 4269831 (1981-05-01), Ferrari et al.
patent: 4370315 (1983-01-01), Greff et al.
patent: 4439432 (1984-03-01), Peat
patent: 4499294 (1985-02-01), Maryanoff
patent: 4508714 (1985-04-01), Cecic et al.
patent: 4517175 (1985-05-01), Iwabuchi et al.
patent: 4720489 (1988-01-01), Shander
patent: 4885289 (1989-12-01), Breuer et al.
patent: 4935231 (1990-06-01), Pigiet
patent: 4935450 (1990-06-01), Cone, Jr.
patent: 5095007 (1992-03-01), Ahluwalia
patent: 5096911 (1992-03-01), Ahluwalia et al.
patent: 5132293 (1992-07-01), Shander et al.
patent: 5143925 (1992-09-01), Shander et al.
patent: 5189212 (1993-02-01), Ruenitz
patent: 5271942 (1993-12-01), Heverhagen
patent: 5300284 (1994-04-01), Wiechers et al.
patent: 5328686 (1994-07-01), Shander et al.
patent: 5362748 (1994-11-01), Schwen et al.
patent: 5364885 (1994-11-01), Ahluwalia et al.
patent: 5411991 (1995-05-01), Shander et al.
patent: 5422371 (1995-06-01), Liao et al.
patent: 5444090 (1995-08-01), Ahluwalia
patent: 5455234 (1995-10-01), Ahluwalia et al.
patent: 5468476 (1995-11-01), Ahluwalia et al.
patent: 5474763 (1995-12-01), Shander et al.
patent: 5554608 (1996-09-01), Ahluwalia et al.
patent: 5645825 (1997-07-01), Hillebrand et al.
patent: 5648394 (1997-07-01), Boxall et al.
patent: 5652273 (1997-07-01), Henry et al.
patent: 5674477 (1997-10-01), Ahluwalia
patent: 5728736 (1998-03-01), Shander et al.
patent: 5776442 (1998-07-01), Ahluwalia
patent: 5824665 (1998-10-01), Henry et al.
patent: 5840752 (1998-11-01), Henry et al.
patent: 5908867 (1999-06-01), Henry et al.
patent: 5939458 (1999-08-01), Henry et al.
patent: 5958946 (1999-09-01), Styczynski et al.
patent: 5962466 (1999-10-01), Styczynski et al.
patent: 6020006 (2000-02-01), Styczynski et al.
patent: 6037326 (2000-03-01), Styczynski et al.
patent: 6060471 (2000-05-01), Styczynski et al.
patent: 6093748 (2000-07-01), Ahluwalia et al.
patent: 6121269 (2000-09-01), Henry et al.
patent: 6218435 (2001-04-01), Henry et al.
patent: 6235737 (2001-05-01), Styczynski et al.
patent: 6239170 (2001-05-01), Ahluwalia et al.
patent: 6248751 (2001-06-01), Ahluwalia et al.
patent: 6284234 (2001-09-01), Niemiec et al.
patent: 6299865 (2001-10-01), Styczynski et al.
patent: 0 413 528 (1990-08-01), None
patent: 0 532 219 (1992-09-01), None
patent: 0 872 248 (1998-10-01), None
patent: 0 943 311 (1999-09-01), None
patent: 0 943 311 (2000-05-01), None
patent: 1 458 349 (1976-12-01), None
patent: 2001026522 (2001-01-01), None
patent: WO 95/33439 (1995-12-01), None
patent: WO 98/02134 (1998-01-01), None
Kuhajda, F.P., et al., “Synthesis and antitumor activity of an inhibitor of fatty acid synthase”, Proc Natl Acad Sci U S A, 2000. 97(7): p. 3450-4.
Lin, S. et al., “Inhibition of 4-hydroxyphenylpyruvate dioxygenase by sethoxydim, a potent inhibitor of acetyl-coenzyme A carboxylase”, Bioorg Med Chem Lett, 1999. 9(4): p. 551-4.
Kennedy, J.A. et al., “Effect of trimetazidine on carnitine palmitoyltransferase-1 in the rat heart”, Cardiovasc Drugs Ther, 1998. 12(4): p. 359-63.
Broadway, N.M., “Novel methylenecyclopropyl-based acyl-CoA dehydrogenase inhibitor”, FEBS Lett, 1998. 437(1-2): p. 122-6.
Botchkarev et al., “A New Role for Neurotrophin-3”, American Journal of Pathology, vol. 153, pp. 785-799, 1998.
Botchkarev et al., “Neurotrophin-3 Involvement in the Regulation of Hair Follicle Morphogenesis”, The Journal of Investigative Dermatology, vol. 111, No. 2 , pp. 279-285, 1998.
Hoffmann et al., “Interleukin-1 β-Induced Inhibition of Hair Growth In Vitro Is Mediated by Cyclic AMP”, The Journal of Investigative Dermatology, vol. 108, pp. 40-42, 1997.
Kennedy et al., “Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiodarone”, Biochem Pharmacol, 1996. 52(2): p. 273-80.
Cummings, J.G. et al., “3-Methyleneoctanoyl-CoA and 3-methyl-trans-2-octenoyl-CoA: two new mechanism-based inhibitors of medium chain acyl-CoA dehydrogenase from pig kidney” Biochemistry, 1994. 33(3): p. 788-97.
Saeed, A., et al., “Carnitine acyltransferase enzymic catalysis requires a positive charge on the carnitine cofactor”, Arch Biochem Biophys, 1993. 305(2): p. 307-12.
Tserng, K.Y. et al., “Spiropentaneacetic acid as a specific inhibitor of medium-chain acyl-CoA dehydrogenase”, Biochemistry, 1991. 30(44): p. 10755-60.
Messenger, Andrew G., “The Control of Hair Growth: An Overview”, The Journal of Investigative Dermatology, vol. 101, No. 1, pp. 4s-9s, 1993.
Weinberg et al., “Reconstitution of Hair Follicle Development In Vitro: Determination of Follicle Formation, Hair Growth, and Hair Quality by Dermal Cells”, The Journal of Investigative Dermatology, vol. 100, pp. 229-236, 1993.
Lilly, K., et al., “Effect of etomoxiryl-CoA on different carnitine acyltransferases”, Biochem Pharmacol, 1992. 43(2): p. 353-61.
Rose-Kahn, G. et al., “Inhibition of rat liver acetyl-CoA carboxylase by beta, beta′-tetramethyl-substituted hexadecanedioic acid”, (MEDICA 16). Biochim Biophys Acta, 1990. 1042(2): p. 259-64.
Kashfi, K., et al., “Inhibition of mitochondrial carnitine palmitoyltransferases by adriamycin and adriamycin analogues”, Biochem Pharmacol, 1990. 40(7): p. 1441-8.
Gandour, R.D., et al., “Hemipalmitoylcarnitinium, a strong competitive inhibitor of purified hepatic carnitine palmitoyltransferase”, Arch Biochem Biophys, 1988. 267(2): p. 515-20.
Olubadewo, J.O. et al., “Effects of 8-N,N-diethylamino-octyl-3,4,5-trimethoxybenzoate (TMB-8) HC1 and verapamil on the metabolism of free fatty acid by hepatocytes”, Biochem Pharmacol, 1988. 37(8): p. 1463-71.
Li, J.X. et al., “4-Bromo-2-octenoic acid specifically inactivates 3-ketoacyl-CoA thiolase and thereby fatty acid oxidation in rat liver mitochondria”, Biochemistry, 1988. 27(16): p. 5995-6000.
Shinagawa, S., et al., “Chemistry and inhibitory activity of long chain fatty acid oxidation of emeriamine and its analogues”, J Med Chem, 1987. 30(8): p. 1458-63.
Cook, G.A., “The hypoglycemic sulfonylureas glyburide and tolbutamide inhibit fatty acid oxidation by inhibiting carnitine palmitoyltransferase”, J Biol Chem, 1987. 262(11): p. 4968-72.
el-Aleem, S.A. et al., “Evaluation of inhibitors of fatty acid oxidation in rat myocytes”, Biochem Pharmacol, 1987. 36(24): p. 4307-12.
Whittington, F.M., et al., “Effect of sodium 2-n-pentadecyl-benzimidazole-5-carboxylate (M & B 35347B), an inhibitor of acetyl-CoA carboxylase, on lipogenesis and fat deposition in obese hyperglycaemic (ob/ob) and lean mice”, Int J Obes, 1987. 11(6): p. 619-29.
Ebling, F. John G., “The Biology of Hair”, Dermatologic Clinics, vol. 5, No. 3, pp. 467-481, 1987.
Jenkins et al., “Antiketogenic and hypoglycemic effects of aminocarnitine and acylaminocarnitines”, Proc Natl Acad Sci U S A, 1986. 83(2): p. 290-4.
Gandour, R.D., et al., “Active-site probes of carnitine acyltransferases. Inhibition of carnitine acetyltransferase by hemiacetylcarnitinium, a reaction intermediate analogue”, Biochem Biophys Res Commun, 1986. 138(2): p. 735-41.
Stephens, T.W., et al., “Two mechanisms produce tissue-specific inhibition of fatty acid oxidation by oxfenicine” Biochem J, 1985. 227(2): p. 651-60.
Bauche, F. et al., “Inhibition in vitro of acyl-CoA dehydrogenases by 2-mercaptoacetate in rat liver mitochondria”, Biochem J, 1983. 215(3): p. 457-64.
Schulz, H., “Metabolism of 4-pentenoic acid and inhibition of thiolase by metabolites of 4-pentenoic acid”, Biochem
Ahluwalia Gurpreet S.
Henry James P.
Hwang Cheng Shine
Shander Douglas
Bolam Brian M.
Hagerty Andrew J.
Lamm Marina
Padmanabhan Sreeni
Rosnell Tara M.
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