Multi-pixel electron microbeam irradiator systems and...

Radiant energy – With charged particle beam deflection or focussing – With target means

Reexamination Certificate

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Reexamination Certificate

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11320515

ABSTRACT:
Multi-pixel electron microbeam irradiator systems and methods are provided with particular applicability for selectively irradiating predetermined cells or cell locations. A multi-pixel electron microbeam irradiator system can include a plurality of individually addressable electron field emitters sealed in a vacuum. The multi-pixel electron microbeam irradiator system can include an anode comprising one or more electron permeable portions corresponding to the plurality of electron field emitters. Further, the multi-pixel electron microbeam irradiator system can include a controller operable to individually control electron extraction from each of the electron field emitters for selectively irradiating predetermined locations such as cells or cell locations.

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Resat et al., “Microbeam developments and applications: A low linear energy transfer perspective,” Cancer and Metastasis Reviews 23: p. 323-331 (2004).
International Search Report for corresponding International Application No. PCT/US05/47066 dated Oct. 6, 2006.

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