Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2007-03-27
2007-03-27
Benzion, Gary (Department: 1637)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C435S006120, C435S069100, C530S387100, C536S023100
Reexamination Certificate
active
09973278
ABSTRACT:
The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
REFERENCES:
patent: 6416973 (2002-07-01), Bakker et al.
patent: 2004/0132085 (2004-07-01), Bakker et al.
patent: 2004/0177391 (2004-09-01), Bakker et al.
patent: 2005/0084900 (2005-04-01), Bakker et al.
patent: WO-99/06548 (1999-02-01), None
patent: WO-99/06557 (1999-02-01), None
patent: WO02/102994 (2002-12-01), None
GenBank GI:5706449 (Aug. 1999).
Lanier et al., “Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells,” Nature 39:703-707, 1998.
Lucas et al., “Massive inflammatory syndrome and lymphocytic immunodeficiency in KARAP/DAP12-transgenic mice,” Eur. J. Immunol 32:2653-2663, 2002.
Bakker et al., “DAP12-Deficient Mice Fail to Develop Autoimmunity Due to Impaired Antigen Priming,” Immunity 13:345-353, 2000.
Geneseq Accession No. AAV83519, Moretta et al., “Human killer cell activatory receptor-associated protein,” Jan. 28, 1998.
EMBL Database, Accession No. AA481924, Hillier, et al., “zv41f05.r1 Soares ovary tumor NbHOT Homo sapiens cDNA clone Image:756255 5′ similar to TR:G498729 G498729 Zinc Finger Protein;, mRNA sequence” (Jun. 24, 1997).
Partial European Search Report for European Patent Application EP 04 00 7560.8 (Jun. 2, 2005).
Bakker et al., “Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells,”Proc. Natl. Acad. Sci. USA, 96:9792-9796 (Aug. 1999).
LaFleur David W.
Rosen Craig A.
Ruben Steven M.
Benzion Gary
Human Genome Sciences Inc.
Human Genome Sciences Inc.
Woolwine Samuel
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