Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent
Reexamination Certificate
2007-07-10
2007-07-10
Parsa, J. (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Chalcogen in the nitrogen containing substituent
Reexamination Certificate
active
11145840
ABSTRACT:
A novel one-stage process for preparing 10α-[4′-(S,S-dioxothiomorpholin-1′-yl)]-10-deoxo-10-dihydroartemisinin (1a) by reacting a compound of the formula (1b)in which X is a halogen atom with thiomorpholine dioxide at a temperature in the range of −30° C. to +20° C. is provided.
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patent: 6649647 (2003-11-01), Haynes et al.
patent: 2005/0119232 (2005-06-01), Haynes
patent: 00/04024 (2000-01-01), None
Johnson J L; Werbel L M: “Synthesis and antileishmanial activity of 6-methoxy-4-methyl-N-'6-(substituted-1-piperazinyl)hexyl!-8-quinolina mines and related compounds” Journal of Medicinal Chemistry, Bd. 26, Nr. 2, 1983, Seiten 185-194, XP002347850.
LANXESS Deutschland GmbH
Miller Michael A.
Parsa J.
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