Pyrido[2,3-d]pyrimidine dichloro-phenyl derivatives

Details Pyrido[2,3-d]pyrimidine dichloro-phenyl derivatives Pyrido[2,3-d]pyrimidine dichloro-phenyl derivatives

2007-03-13

2007-03-13

Rao, Deepak (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S279000

Reexamination Certificate

active

11079623

ABSTRACT:
The invention describes compounds of the general formula Ia process for their manufacture, compositions containing them and their manufacture as well as the use of these compounds as pharmaceutically active agents. These compounds show activity as protein kinase inhibitors, in particular src family tyrosine kinase inhibitors, and may therefore be useful for the treatment of diseases mediated by said tyrosine kinases.

REFERENCES:
patent: WO 96/15128 (1996-05-01), None
patent: WO/1996/15128 (1996-05-01), None
patent: WO 02/090360 (2002-11-01), None
patent: WO/2002/090360 (2002-11-01), None
patent: WO 03/000011 (2003-01-01), None
Margaret C. Frame, Biochimica et Biophysica Acta-Reviews on Cancer, vol. 1602, Issue 2 , Jun. 21, 2002, pp. 114-130.
Wolff, Manfred E. “Burger's Medicinal Chemistry, 5ed, Part I,”, John Wiley & Sons, 1995, pp. 975-977.
Banker, G.S. et al, “Modern Pharmaceutics, 3ed.”, Marcel Dekker, New York, 1996, pp. 451 and 596.
Noble, M.E.M. et al, Science, vol. 303, pp. 1800-1805.
Bastin et al., Organic Proc. Res. Dev., 4, pp. 427-435 (2000).
Biscardi et al., Adv. Cancer Res., 76, pp. 61-119 (2000).
Merrifield, Fed. Proc. Fed. Amer. Soc. Exp. Biol., 21, pp. 412 (1962).
Susa et al., Trends Pharmacoal. Sci., 21, pp. 489-495 (2000).

Affiliated with

Also associated with

Rating

Pyrido[2,3-d]pyrimidine dichloro-phenyl derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pyrido[2,3-d]pyrimidine dichloro-phenyl derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrido[2,3-d]pyrimidine dichloro-phenyl derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3767950