Method and kit for following neurodegenerative diseases

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C436S507000, C436S513000

Reexamination Certificate

active

10471788

ABSTRACT:
The invention relates to a method for detecting and supervising neurodegenerative diseases, which consists in detecting the presence of antibodies of the A-isotype and/or M-isotype which are directed against the antigens which are associated with these diseases.The invention also relates to a kit for the implementation of this method.

REFERENCES:
patent: 5047330 (1991-09-01), Grassi et al.
patent: 621479 (1994-10-01), None
patent: 2 822 238 (2002-09-01), None
Mark, MH. Lumping and splitting the parkinson plus syndromes. Dementia with lewy bodies, multiple system atrophy, progressive supranuclear palsy, and cortical-basal ganglionic degeneration. Neurologic Clinics, 2001, 19(3): 607-627.
Holmberg, B. CSF-neurofilament and levodopa tests combined with discriminant analysis may contribute to the differential diagnosis of Parkinsonian syndromes. Parkinsonism & Related Disorders, 2001, 8: 23-31.
Amara A et al. Autoantibodies to malondialdehyde-modified epitope in connective tissue disease and vasculitudes. Clin. Exp. Immunol, 1995, 101: 233-238.
Boullerne Al et al. Circulating antibodies directed against conjugated fatty acids in sera of patients with multiple sclerosis. J. Neuroimmunol, 1996, 65: 75-81.
Geffard M et al. Circulating antibodies directed against NO-modified self-antigens in chronic neurological and rhemumatismal diseases. Immunoanal Biol Spec, 1998, 13: 209-217 (in French, translated by The McElroy Translation Co. for the USPTO).
Hughes Le et al. Antibody responses toAcinetobacterspp. andPseudomonas aeruginosain multiple sclerosis: Prospects for diagnosis using the myelin-Acinetobacter-neurofilament antibody index. Clin. Diag. Lab. Immunol, 2001, 8(6): 1181-1188.
Analytical Chemistry 57 (1985) 1170-1173.
Amara A., Chaugier C. and Geffard M. Autoantibodies directed against conjugated fatty acids in sera of HIV-1 infected patients. AIDS, (1994 a) 8, 711-713.
Amara A., Chaugier C., Ragnaud J.-M. and Geffard M. Circulating autoantibodies directed against conjugated fatty acids in sera of HIV-1 infected patients. Clinical and Experimental Immunology, (1994 b) 96, 379-383.
Boullerne A., Petry K.G., Meynard M. and Geffard M. Indirect evidence for NO involvement in multiple sclerosis by characterization of circulating antibodies directed against conjugated S-nitrosocysteine. J. of Neuroimmunol., (1995) 60, 117-124.
Brochet B., Faiderbe S., Audhuy S., Gosset I., Geffard M. and Orgogozo J.M. Antibodies against phosphatidylinositol in multiple sclerosis. Current Concepts in Multiple Sclerosis—proceedings of the 6thcongress of the ECTRIMS. (Wietholter M., Dichgans J.). Mertin J., Eds Excerpta Medica, Amsterdam, (1991) 97-102.
Constans J., Conri C., Pellegrin J.L., Sergeant C., Simonoff M., Peuchant E., Dubourg L., Thomas M.J., Pellegrin I., Brossard G., Barbeau P., Amara A., Geffard M., Clerc M., Fleury H. and Leng B. Stress oxydatif and infection a VIH : un concept a preciser and une voie therapeutique a explorer (<<Oxidative stress and infection with HIV : a concept to be specified and a therapeutic route to be explored>>). Annales de Medecine Interne, (1995) 146, 514-520.
Daverat P., Geffard M. and Orgogozo J.M. Identification and characterization of anti-conjugated azelaic acid antibodies in multiple sclerosis. J. of Neuroimmunology, (1989), 22, 129-134.
Faiderbe S., Chagnaud J.L., Wafflart J. and Geffard M. Autoanticorps diriges contre un phospholipide membranaire dans les serums de malades porteurs de tumeurs malignes. (<<Auto-antibodies directed against a membrane phospholipid in the sera of ill subjects having malignant tumours>>). CRAS, (1990) 310, 49-52.
Maneta-Peyret L., Daverat P., Geffard M., Cassgane C. and Orgogozo J.M. Natural seric anti-fatty acid antibodies in multiple sclerosis. Neurosc. Letters, (1987) 80, 235-239.
Souan M.L. Geffard M., Lebrun-Grandie P. and Orgogozo J.M. Detection of anti-acetylcholine antibodies in myasthenic patients. Neurosc. Letters. (1986) 64, 23-28.

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