D-tagatose as an anti-biofilm agent

Chemical apparatus and process disinfecting – deodorizing – preser – Process disinfecting – preserving – deodorizing – or sterilizing – Process of storage or protection

Reexamination Certificate

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C514S023000

Reexamination Certificate

active

10223480

ABSTRACT:
There is disclosed a method for disrupting biofilm and for inhibiting biofilm formation in an aqueous environment that comprises contacting said environment with an effective amount of D-tagatose.

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Bertelsen et al., Food Science and Technology, vol. 112, 2001.
Shaniztki et al., “Identification of Fusobacterium nucleatum PK 1594 Glactose-Binding Adhesin Which Mediates Coaggregation with Periopathogenic Bacteria and Hemagglutination”, Infect. Immun., 65:5231-5237, 1997.
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Paul E. Kolenbrander et al., “Inhibiton of Coaggregation between Fusobacterium nucleatum and Porphyromonas (Bacteroides) ginivalis by Lactose and Related Sugars”, Laboratory of Microbial Ecology, National Institute of Dental Research, Bethesda, MD, vol. 57, No. 10, pp. 3204-3209.
Bertelsen et al., “Tagatose”, Food Science and Technology, vol. 12, pp. 105-127, 2001.

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