Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Reexamination Certificate
2007-05-22
2007-05-22
Achutamurthy, P. (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
C435S440000, C435S069100, C435S071100, C435S004000, C435S006120, C435S252300, C435S320100, C435S023000, C435S023000
Reexamination Certificate
active
10375909
ABSTRACT:
Glucose oxidase enzymes are provided, including novel variants of galactose oxidase enzymes. The polynucleotides that encode these novel variants can be expressed in recombinant host cell expression systems. The novel variant oxidase enzymes are capable of oxidizing compounds towards which wild-type galactose oxidase (e.g. D-galactose: oxygen 6-oxidoreductase, GAO; EC 1.1.3.9) has little or no activity. Preferred galactose oxidase variants are those which that have improved capability to oxidize secondary alcohols and/or D-glucose relative to the wild-type enzyme.
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Arnold Frances H.
Petrounia Ioanna P.
Sun Lian-Hong
Achutamurthy P.
California Institute of Technology
DLA Piper (US) LLP
Pak Yong D.
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