Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Reexamination Certificate
2007-07-31
2007-07-31
Ungar, Susan (Department: 1645)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
C424S190100, C435S069700, C536S023700, C530S350000, C530S300000
Reexamination Certificate
active
10066551
ABSTRACT:
The present invention is directed to novel polypeptides, polynucleotides and vaccines for use againstNeisseria gonorrhoeaecolonization or infection. The vaccines contain an immunogenic amount of a neisserial protein.
REFERENCES:
patent: 4533630 (1985-08-01), Wilkins et al.
patent: 4554101 (1985-11-01), Hopp
patent: 4559157 (1985-12-01), Smith et al.
patent: 4608392 (1986-08-01), Jacquet et al.
patent: 4820508 (1989-04-01), Wortzman
patent: 4873192 (1989-10-01), Kunkel
patent: 4938949 (1990-07-01), Borch et al.
patent: 4992478 (1991-02-01), Geria
patent: 2004/0253222 (2004-12-01), Apicella et al.
patent: 0 184 187 (1986-06-01), None
patent: WO-98/02547 (1998-01-01), None
patent: WO-99/24578 (1999-05-01), None
patent: WO-99/57280 (1999-11-01), None
patent: WO-00/71725 (2000-11-01), None
Paz et al 1995, Microbiology 141, 913-920.
Accession-No. AAY 75751.
Accession No. B81859.
Cann et al 1989, J.Med.Microbiology 30, 23-30.
Barritt et al, Infection and Immunity 1987, 55:2026-2031.
Caron, Emmanuelle, et al. , “Identification of Two Distinct Mechanisms of Phagocytosis Controlled by Different Pho GTPases”,Science, vol. 282, (Nov. 27, 1998),1717-1721.
Christodoulides, Myron, et al. , “Interaction of primary human endometrial cells withNeisseria gonorrhoeaeexpressing green flourescent protein”,Molecular Microbiology, vol. 35, (2000),32-43.
Cooper, Neil, “Complement evasion strategies of microorganisms”,Immunology Today, vol. 12, No. 9, (1991),327-331.
De La Paz, Helen, et al. , “Effect of sialyation of lipopolysaccharide ofNeisseria gonorrhoeaeon recognition and complement-mediated killing by monoclonal antibodies directed against different outer-membrane antigens”,Microbiology, vol. 141, No. 4, (Apr. 1995),913-920.
Densen, Peter, et al. ,“Dissemination of Gonococcal Infection is Associated with Delayed Stimulation of Complement-Dependent Neutrophil Chemotaxis In Vitro”,Infection and Immunity, vol. 38, No. 2, (Nov. 1982),563-572.
Densen, Peter, “Interaction of Complement withNeisseria meningitidisandNeisseria gonorrhoeae”, Clinical Microbiology Reviews, vol. 2, (Apr. 1989),S11-S17.
Edwards, J.L., et al., “Neiserria gonorrhoeaeElicits Membrane Ruffling and Cytoskeletal Rearrangements upon Infection of Primary Human Endocervical and Ectocervical Cells”,Infection and Immunity, 68, (2000),5354-5363.
Frank, Michael, et al. , “Complement Interactions and Functions, The role of complement in inflammation and phagocytosis”,Immunology Today, vol. 12, No. 9, (1991),322-326.
Harvey, Hillery, et al. , “Ultrastructural Analysis of Primary Human Urethral Epithelial Cell Cultures Infected withNeisseria gonorrhoeae”, Infection and Immunity, vol. 65, No. 6, (Jun. 1997),2420-2427.
Hayashi, Tomoko, et al. , “Binding of the 68-Kilodalton Protein ofMycobacterium aviumto αvβ3on Human Monocyte-Derived Macrophages Enhances Complement Receptor Type 3 Expression”,Infection and Immunity, vol. 65, No. 4, (Apr. 1997),1211-1216.
Hussain, L.A. , et al. ,“Investigation of the complement receptor 3 (CD11b/CD18) in human rectal epithelium”,Clinical and Experimental Immunology, vol. 102, (1995),384-388.
Hynes, Richard,“Integrins: A Family of Cell Surface Receptors”,Cell, vol. 48, No. 4, (Feb. 27, 1987), 549-554.
Ingalls, Robin, et al. ,“The CD11/CD18 Integrins: Characterization of Three Novel LPS Signling Receptors”,Prog. Clin. Biol. Res., vol. 397, (1998),107-117.
Jarvis, Gary, et al. ,“Invasion of Human Mucosal Epithelial Cells byNeisseria gonorrhoeaeUpregulates Expression on Intercellular Adhesion Molecule 1 (ICAM-1)”,Infection and Immunity, vol. 67, No. 3, (Mar. 1999),1149-1156.
Jerse, Ann, et al. ,“Adhesion and invasion by the pathogenicneisseria”, Trends in Microbiology, vol. 5, No. 6, (Jun. 1997),217-221.
Jones, J.L.,et al. ,“Integrins: a role as cell signalling molecules”,Journal of Clinical Pathology: Molecular Pathology, vol. 52, (1999),208-213.
Jones, Samuel, et al. ,“Two Signaling Mechanisms for Activation of αMβ2Avidity in Polymorphonuclear Neutrophils”,Journal of Biological Chemistry, vol. 273, No. 17, (Apr. 24, 1998),10556-10566.
Kishimoto, Takashi, et al. ,“The Leukocyte Integrins”,Advances in Immunology, vol. 46, (1989),149-182.
Kragsbjerg, P., et al. ,“The effects of liveNeisseria menigitidisand tumour necrosis factor-α on neutrophil oxidative burst and β2-integrin expression”,APMIS, vol. 108, (2000),276-282.
Mcquillen, Daniel, et al. ,“Complement Processing and Immunoglobulin Binding toNeisseria gonorrhoeaeDetermined In Vitro Simulates In Vivo Effects”,The Journal of Infectious Diseases, vol. 179, No. 1, (Jan. 1999), 124-135.
Mesri, Mehdi, et al. ,“Dual regulation of Ligand Binding by CD11b I Domain”,The Journal of Biological Chemistry, vol. 273, No. 2, (Jan. 9, 1998),744-748.
Meyer, Thomas,“Pathogenic Neisseriae: Complexity of Pathogen—Host Cell Interplay”,Clinical Infectious Diseases, vol. 28, No. 3, (Mar. 1999),433-441.
Mosser, David, et al. ,“The third component of complement (C3) is responsible for the intracellular survival ofLeishmania major”, Nature, vol. 327, No. 6210, (May 28, 1987),329-331.
Nassif, Xavier, et al. ,“Interaction of Pathogenic Neisseriae with Nonphagocyctic Cells”,Clinical Microbiology Reviews, (Jul. 1995),376-388.
Nassif, Xavier, et al. ,“Interactions of PathogenicNeisseriawith host cells. Is it possible to assemble the puzzle?”,Molecular Microbiology, vol. 32, No. 6, (Jun. 1999),1124-1132.
Naumann, Michael, et al. ,“Host cell interactions and Signalling withNeisseria gonorrhoeae”, Curr. Opin. Microbiol., vol. 2, (1999),62-70.
Ram, Sanjay, et al. ,“A Novel Sialic Acid Binding Site on Factor H Mediates Serum Resistance of SialylatedNeisseria gonorrhoeae”, Journal of Experimental Medicine, vol. 187, No. 5, (Mar. 2, 1998),743-752.
Ram, S., et al. ,“The contrasting mechanisms of serum resistance ofNeisseria gonorrhoeaeand group BNeisseria meningitidis”, Molecular Immunology, vol. 36, No. 13-14, (1999),915-928.
Van Kooyk, Yvette, et al. ,“The Actin Cytoskeleton Regulates LFA-1 Ligand Binding through Avidity Rather than Affinity Changes”,The Journal of Biological Chemistry, vol. 274, No. 38, (Sep. 17, 1999),26869-26877.
Vogel, Ulrich, et al. ,“Mechanism of neisserial serum resistance”,Molecular Microbiology, vol. 32, No. 6, (Jun. 1999),1133-1139.
Wurzner, Reinhard, “Evasion of pathogens by avoiding recognition or eradication by complement, in a part via molecular mimicry”,Molecular Immunology, vol. 36, (1999),249-260.
Edwards, J..L. , et al. ,“Complement Receptor Type 3 (CR3) on Primary Cervical Epithelial Cells Serves as a Receptor forNeisseria Gonorrhoeae”, Abstracts of the 101st General Meeting of the American Society for Microbiology, Orlando, FL,(May 20-24, 2001),p. 303.
Krishnan Thankavel et al., “Localization of a Domain in the FimH Adhesin ofEscherichia coliType 1 Fimbriae Capable of Receptor Recognition and Use of a Domain-specific antibody to Confer Protection against Experimental Urinary Tract Infection”,J. Clin. Invest., vol. 100, No. 5, Sep. 1997, pp. 1123-1136.
P. M. Steed et al., “Intracellular Signaling by Phospholipase D as A Therapeutic Target”,Current Pharmaceutical Biotechnology, 2001, vol. 2, 241-256.
Edwards, J. L., et al., “The Role of Complement Receptor 3 (CR3) inNeisseria gonorrhoeaeInfection of Human Cervical Epithelia”,Cellular Microbiology, 3, (Sep. 2001), 611-622.
Fijen, C. A., et al., “The Role of Fc-gamma Receptor Polymorphisms and C3 in the Immune Defence AgainstNeisseria meningitidisin Complement-Deficient Individuals”,Clinical and Experimental Immunology, 120, (May 2000), 338-345.
Cohen et al.,Human Experimenta
Apicella Michael A.
Edwards Jennifer L.
Gibson Bradford W.
Scheffler Karoline
Baskar Padma
Ungar Susan
University of Iowa Research Foundation
Viksnins Harris & Padys PLLP
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