Substituted bicyclic pyrimidinones as a mitotic kinesin KSP...

Details Substituted bicyclic pyrimidinones as a mitotic kinesin KSP... Substituted bicyclic pyrimidinones as a mitotic kinesin KSP...

2007-03-20

2007-03-20

Berch, Mark L. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S116000, C544S230000, C544S253000, C540S504000, C540S460000, C540S470000, C540S492000, C540S575000, C514S266300, C514S234500, C514S218000, C514S258100

Reexamination Certificate

active

11410341

ABSTRACT:
The present invention relates to cycloalkylpyrimidinone compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.

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