Intravenous valproate for acute treatment of migraine headache

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

Reexamination Certificate

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C424S400000, C514S557000

Reexamination Certificate

active

11173922

ABSTRACT:
The present invention features a novel therapy for effecting acute treatment of migraine headache. The therapy involves intravenous administration of valproate and is equal to and in some respects superior to previously-known therapies for abortive treatment of prolonged moderate to severe acute migraine headache.

REFERENCES:
patent: 5102913 (1992-04-01), Halikas
patent: 5432176 (1995-07-01), Walser
patent: 5767117 (1998-06-01), Moskowitz
patent: WO-99/66920 (1999-12-01), None
patent: WO-00/66109 (2000-11-01), None
Welch, “Drug Therapy: Drug Therapy Migraiine,” The New England Journal of Medicine, Nov. 11, 1993, pp. 1476-1483.
Arnold, G., et al., “Valproic acid in the prophylactic treatment of migraine,”Nervenarzt, vol. 69(10):913-918 (1998).
Curtrer, F.M., et al., “Possible mechanisms of valproate in migraine prophylaxis,”Cephalagia, vol. 17:93-100 (1997).
Edwards, Keith R., et al., “Sodium valproate for the treatment of chronic daily headaches,”Cephalagia, vol. 19:453 (1999), Abstract No. VI-G5-1.
Edwards, Keith R., et al., “Acute Treatment of Migraine Headeach with Intravenous Valproate (Depecon),”Epilepsia, vol. 40(Suppl. 7):143 (1999), Abstract No. 2,240.
Edwards, Keith R, et al., “Intravenous valproate for abortive treatment of acute migraine headache. Is there an anti-convulsant mechanism?”Epilepsia, vol. 40(Suppl. 2):36 (1999).
Edwards, Keith R, “Intravenous valproate for acute treatment of migraine headache,”Cephalalgia, vol. 19:356 (1999), Abstract No. II-GI-7.
Hering, R., et al., “Sodium valproate in the prophylactic treatment of migraine: a double-blind study versus placebo,”Cephalalgia, vol. 12:81-84 (1992).
Jensen, R., et al., “Sodium valproate has a prophylactic effect in migraine worhour aura: a triple-blind, placebo-controlled crossover study,”Neurology, vol. 44:647-651 (1994).
Mathew, Ninan T., et al., “Repetitive intravenous administration of valproate sodium in intractable migraine: Comparison with intravenous Dihydroegotamine (DHE).”Neurology, vol. 54(Suppl. 3):A22 (2000).
Mathew, Ninan T., et al., “Migraine prophylaxis with divalproex,”Arch Neurol, vol. 17:281-286 (1995).
Ramsay, R.E., et al., “The tolerability and safty of valproate sodium injectino given as an intravenous infusion,”Journal of Epilepsy, vol. 10(4):187-193 (1997).
Tran, Bihn N., et al., “Can valproate prevent migraine headache?”Journal of Pharmacy Technology, vol. 13(4):163-168 (1997).
“Intravenous valproate sodium for intractible mitraine,”Journal of Pharmacy Technology, vol. 16(4):161 (2000).
Edwards, Keith R., et al., “Intravenous Valproate For Acute Treatment Of Migraine Headache,”Headache, vol. 39(5):201 (1999), Poster #76.
Kailasam, J., et al., “Intravenous Valproate Sodium (Depacon) Aborts Migraine Rapidly: A Preliminary Report,”Headache, vol. 39(5):168-169 (1999).
Depacon™: Valproate Sodium Injection, Abbott Laboratories 06-9798-R2, Jan. 1998; (No. 1564).

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