Benzothiazine and benzothiadiazine compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C544S012000

Reexamination Certificate

active

10499082

ABSTRACT:
Compounds of formula (I):wherein:R1represents hydroxy or RCO—O—,R2represents hydrogen, halogen, hydroxy or R′CO—O,R, R′, which may be identical or different, represent linear or branched (C1-C6)alkyl optionally substituted by aryl, linear or branched (C2-C6)alkenyl optionally substituted by aryl, linear or branched (C1-C6)perhaloalkyl, (C3-C7)cycloalkyl, adamantyl, aryl or heteroaryl,R3represents hydrogen, linear or branched (C1-C6)alkyl or (C3-C7)cycloalkyl,A represents CR4R5or NR4,R4represents hydrogen or linear or branched (C1-C6)alkyl,their isomers and also their addition salts with a pharmaceutically acceptable acid or base.Medicaments.

REFERENCES:
patent: WO 9321170 (1993-10-01), None
patent: WO 9812185 (1998-03-01), None
patent: WO 9942456 (1999-08-01), None
patent: WO 9942456 (1999-08-01), None
patent: WO 0140210 (2001-07-01), None
Alt et al. Current Pharmaceutical Design, 2005, 11, 1511-1527.
Black et al Psychopharmacology (2005) 179: 154-163.
Phillips et al. Bioorganic & Medicinal Chemistry 10 (2002) 1229-1248.
Maskell, et al.,Br. J. Pharmacol, 2003, 140, 1313-1319.
Aracava, et al.,JPET, 2005, 312, 1195-1250.
Advokat, et al.,Neurosci. Biobehav. Rev., 1992, 16, 13-24.
Danysz, et al.,Behav. Pharmacol., 1995, 6, 455-474.
Lynch,Neurobiology of Learning and Memory, 1998, 70, 82-100.
Robbins, et al.,TRENDS in Pharmacological Sciences, 2006, 27 (3), 141-148.
Bliss, et al.,Nature, 1993, 361, 31-39.
Ito, et al.,Journal of Physiology, 1990, 424, 533-543.
Cumin, et al.,Psychopharmacology, 1982, 78, 104-111.
Arai, et al.,Brain Res., 1994, 638, 343-346.
Miu, et al.,Neuropharmacol., 2001, 40, 976-983.
Staubli, et al.,Proc. Natl. Acad. Sci., 1994, 91, 777-781.
Lebrun, et al.,European Journal of Pharmacology, 2000, 401, 205-212.
Rao, et al.,Neuroscience Letters, 2001, 298, 183-186.
Thompson, et al.,Proc. Natl. Acad. Sci., 1995, 92, 7667-7671.
Buccafusco, et al.,Neuropharmacol., 2004, 46, 10-22.
Porrino, et al.,PLOS Biology, 2005, 3 (9), 1639-1652.
Ingvar, et al.,Exp. Neurol., 1997, 146, 553-559.
Lynch, et al.,Exp. Neurol., 1997, 145, 89-92.
Baudry,Neurobiology of Learning and Memory, 2001, 76, 284-297.
Day, et al.,Nature, 2003, 424, 205-209.
Lynch,Current Opinion in Pharmacology, 2006, 6, 82-88.
Lin, et al.,Brain Research, 2002, 955, 164-173.
Desai, et al.,Neuropharmacology, 1995, 34 (2), 141-147.
Lockhart, et al.,European Journal of Pharmacology, 2000, 401, 145-153.
Jhee, et al.,J. Clin. Pharmacol., 2006, 46, 424-432.
Roger, et al.,Soc. Neurosci. Abstr., 2004, Abstract No. 219.11.
Dicou, et al.,Brain Research, 2003, 970, 221-225.
Bahr, et al.,Exp. Neurol., 2002, 174, 37-47.
Murray, et al.,JPET, 2003, 306, 752-762.
O'Neill, et al.,European Journal of Pharmacology, 2004, 486, 163-174.
O'Neill, et al.,CNS Drug Rev., 2005, 11 (1), 77-96.
Bai, et al.,Neuropharmacology, 2003, 44, 1013-1021.
Lauterborn, et al.,J. of Neuroscience, 2000, 20 (1), 8-21.
Carrie, et al.,Soc. Neurosci. Abstr., 2005, Abstract No. 1018.4.
Lockhart, et al.,Soc. Neurosci. Abstr., 2004, Abstract No. 92.12.
Munoz, et al.,Soc. Neurosci. Abstr., 2004, Abstract No. 85.13.
Nibuya, et al.,J. of Neuroscience, 1995, 15 (11), 7539-7547.
Dias, et al.,Neuropharmacology, 2003, 45, 553-563.
Alt, et al.,Curr. Pharm. Des., 2005, 11 (12), 1511-1527.
Alt, et al.,Biochemical Pharmacology, 2006, 71, 1273-1288.
Nakamura, et al.,Psychopharmacology, 2001, 158, 205-212.
Li, et al.,Neuropharmacology, 2001, 40, 1028-1033.
Knapp, et al.,European Journal of Pharmacology, 2002, 440, 27-35.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Benzothiazine and benzothiadiazine compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Benzothiazine and benzothiadiazine compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzothiazine and benzothiadiazine compounds will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3753038

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.