Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2007-07-03
2007-07-03
Lilling, Herbert J. (Department: 1657)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S007200, C435S007210, C435S007400, C435S015000, C435S016000, C435S017000, C435S018000, C435S019000, C435S020000, C435S021000, C435S022000, C435S023000, C435S024000, C435S025000, C435S026000, C435S027000, C435S028000
Reexamination Certificate
active
10855952
ABSTRACT:
This invention has as its object a method for detecting catalytic activity of a sample, characterized in that it comprises: the incubation of a substrate (S) with the sample that may have the catalytic activity that it is desired to detect, the addition of a reagent (X) that can react either with a chemical group of unconsumed substrate (S) or with a chemical group of product (P) that is formed after an incubation period with the sample, the addition of a developer (R) that can react with reagent (X), and the detection of the transformation of developer (R).
REFERENCES:
patent: 4277561 (1981-07-01), Monget et al.
patent: 4603108 (1986-07-01), Bascomb
patent: 4778757 (1988-10-01), Teshima et al.
patent: 5122602 (1992-06-01), Corey et al.
patent: 5162203 (1992-11-01), Vallee
patent: 5196312 (1993-03-01), Miike et al.
patent: 5583217 (1996-12-01), Quante et al.
patent: 5846754 (1998-12-01), Pugia et al.
patent: 6455268 (2002-09-01), Jarnigan et al.
patent: 0 317 243 (1989-05-01), None
patent: 0 451 775 (1991-10-01), None
patent: 0 796 854 (1997-09-01), None
patent: 0 810 290 (1997-12-01), None
patent: WO 01 36662 (2001-05-01), None
patent: WO 01/36662 (2001-05-01), None
patent: WO 01/60986 (2001-08-01), None
patent: WO 01/61041 (2001-08-01), None
patent: WO 01/92563 (2001-12-01), None
Holzwarth et al., IR-thermographische erkennung katalytischer aktivitat in kombinatorischen bibliotheken heterogener katalysatoren, Angew. Chem. 1998, 110, Nr. 19, pp. 2788-2792.
Reetz et al., Eine methode zum high-throughput-screening von enantioselektiven katalysatoren, Angew. Chem. 1999, 111, Nr. 12, pp. 1872-1875.
Reetz et al., IR-Thermographie-Screening von thermoneutralen oder endothermen reaktionen: die ringschluss-Olefin-Metathese, Angew. Chem. 2000, 112, Nr. 7, pp. 1294-1298.
Reetz et al., IR-Thermographic screening of thermoneutral or endothermic transformations: The ring-closing olefin metathesis reaction, Angew. Chew. Int. Ed. 2000, 39, No. 7, pp. 1236-1239.
Badalassi et al., A versatile periodate-coupled flurogenic assay for hydrolytic enzymes, Angew. Chem. Int. Ed. 2000, 39, No. 22, pp. 4067-4070.
El-Kommos et al., Spectrophotometric Determination of some catecholamine drugs using metaperiodate, J. Assoc. Off. Anal. Chem. (vol. 73, No. 4, 1990), pp. 516-520.
Firestine et al., Using an araC-based three-hybrid system to detect biocatalysts in vivo, Nature Biotechnology, vol. 18, May 2000, pp. 544-547.
Klein et al., Enantioselective flurogenic assy of acetate hydrolysis for detecting lipase catalytic antibodies, Helvetica Chimica Acta, vol. 82 (1999), pp. 400-407.
Millar et al., Sex attractant pheromone of the pecan nut casebearer (lepidoptera: pyralidae), Bioorganic & Medicinal Chemistry, vol. 4, No. 3, pp. 331-339, 1996.
Moris-Varas et al., Visualization of enzyme-catalyzed reactions using pH indicators: rapid screening of hydrolase libraries and estimation of the enantioselectivity, Bioorganic & Medicinal Chemistry 7 (1999) pp. 2183-2188.
Suzuki, 4, 8 Dimethyldecanal: The aggregation pheromone of the flour beetles,Tribolium castaneumandT. confusum(Coleoptera: Tenebrionidae), Agric. Biol. Chem., 44, (10), pp. 25-19-2520, 1980.
Demirjian et al., Screening for novel enzymes, Top. Curr. Chem. (1999), vol. 200, pp. 1-25.
Jourdain et al., A stereoselective flurogenic assay for aldolases: Detection of an anti-selective aldolase catalytic antibody, Tetrahedron Letters 39 (1998), pp. 9415-9418.
Taran et al., Competitive immunoassay (Cat-EIA), a helpful technique for catalytic antibody detection, Part I, Tetrahedron Letters 40 (1999), pp. 1887-1890.
Matta et al., A rapid synthesis ofp-nitrophenyl 2-O-α-L-fucopyranosyl-β-D-galactopyranoside, Carbohydrate Research, 90 (1981), C1-C3.
N. Jourdian, R. Pérez Carlón, J.-L. Reymond, “A Stereoselective Fluorogenic Assay for Aldolase: Detection of an Anti-Selective Aldolase Catalytic Antibody”, Tetrahedron Letters, NL, (1998), vol. 39, pp. 9415-9418.
G. Klein, J.-L. Reymond, An Enantioselective Fluorometric Assay for Alcohol Dehydrogenases Using Albumin-Catalyzed beta-Elimination of Umbelliferone, Bioorganic & Medicinal Chemistry Letters, (1998), vol. 8, pp. 1113-1116.
G-G. Chang, M-S Shiao, K-R Lee and J-J Wu, “Modification of human placental alkaline phosphatase by periodate—oxidized 1, N6 ethenoadenosine monophosphate”, Biochem. J. (1990), pp. 683-690, vol. 273, Issue No. 3.
X-J. Chen, A. Archelas, R. Furstoss, Microbial Transformations. 27. The First Examples for Preparative-Scale Enantioselective or Diastereoselective Epoxide Hydrolyses Using Microorganisms. An Unequivocal Access to All Four Bisabolol Stereoisomers, J. Org. Chem. (1993), vol. 58, pp. 5528-5532, American Chemical Society.
Harris, Jennifer et al., “Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries”, PNAS (Jul. 5, 2000), pp. 7754-7759, vol. 97, No. 14.
M. T. Reetz, K.-E. Jaeger, “Superior Biocatalysts by Directed Evolution”, Topics in Current Chemistry (1999), vol. 200, p. 31-57.
Geymayer, et al., “A General Fluorogenic Assay for Catalysis using Antibody Sensors”, Chem. Eur. J., vol. 5, No. 3, p. 1006-1012, 1999.
Carlon, et al., “Fluorogenic Polypropionate fragments for detecting Steroselective Algolases”, Chem. Eur. J., vol. 6, No. 22, p. 4154-4162, 2000.
Gruninger-Leitch, et al., “Identification of beta-secretase-like activity using a mass spectrometry-based assay sysytem”, Nature Biotechnology, vol. 18, p. 66-70, 2000.
Moris-Varas, et al., “Visualization of Enzume-Catalyzed Reactionsusing pH indicators: Rapid Screening of Hydrolase Libraries and Estimation of the Enantioselectivity”, Bioorganic andMedicinal Chemistry, vol. 7, p. 2183-2188, 1999.
O'Brien, M. et al., “Enzymatic Profile ofPseudomonas maltophilia”, Journal of Clinical Microbiology (Sep. 1982), pp. 417-421, vol. 16, No. 3.
Ronald G. Harvey, et al., “Synthesis of the Tumorigenic 3,4-Dihydrodiol Metabolites of Dibenz[a, j]lanthracene and 7,14-Dimet hydibenza[a, j]anthracene”, J. Med. Chem., vol. 31, p. 1308-1312, 1988.
Nogare, et al., “Determination of Acetaldehyde and Acetone by the Iodoform Reaction”, Anal. Chem., vol. 23, p. 1473-1478, 1951.
F. Badalassi, D. Wahler, G. Klein, P. Crotti, J-L Reymond, “A Versatile Periodate-Coupled Flourogenic Assay for Hydrolytic Enzymes”, Angewandte Chemie. International Edition, Nov. 17, 2000, pp. 4067-4070, vol. 39, Issue No. 22.
D. C. Demirjian, P. C. Shah, F. Moris-Varas, “Screening for Novel Enzymes”, Topics in Current Chemistry (1999), vol. 200, pp. 1-29.
S. Hanessian, T. Takamoto, R. Massé, G. Patil, “Aminoglycoside antibiotics: chemical conversion of neomycin B, paromycin, and lividomycin B into bioactive pseudosaccharides”. Can. J. Chem. (1978), vol. 56, Issue No. 11, pp. 1482-1491.
M. T. Reetz, G. Lohmer, R. Schwickardi, “A New Catalyst System for the Heck Reaction of Unreactive Aryl Halides”, Angewandte Chemie. International Edition (1998), vol. 37, Issue No. 4, pp. 481-483.
C. A. Roeschlaub, N. L. Maidwell, M. R. Rezai, P. G. Sammes, “A fluorescent probe for the detection of NAD(P)H”, Chemical Communications (1999), pp. 1637-1638.
T. Suzuki, “4,8-Dimethyldecanal: The Aggregation Pheromone of the Flour Beetles, Tribolim castaneum and T.confusum (Coleoptera: Tenebrionidae)”, Agric. Biol. Chem., (1980), vol. 44, pp. 2519-2520.
C. A. G. M. Weijers, A. L. Botes, M. S. Van Dyk, J. A. M. De Bont, “Enantioselective hydroysis of unbranched aliphatic 1,2-epoxides by Rhodatorula glutinis”, Tetrahedron Asymmetry (1998), vol. 9, pp. 467-473.
J.G. Millar, A.E. Knudson, S. McElfresh, R.Gries, G. Gries, J.H. Davis). Bioorganic & Medicinal Chemistry, (1996), vol. 4, Issue No. 3, pp. 331-339.
G. Klein, J.-L. Reymond, “Enantioselection Fluorogenic Assay of Acetate Hydrolysis for Detecting Lipase Catalytic Antibodies”, Helve
Reymond Jean-Louis
Wahler Denis
Hunton & Williams LLP
Lilling Herbert J.
Proteus SA
Universite de Berne
LandOfFree
Method for detecting catalytic activity does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for detecting catalytic activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for detecting catalytic activity will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3749604