Method of preparing 2-deoxyribose 5-phosphate

Details Method of preparing 2-deoxyribose 5-phosphate Method of preparing 2-deoxyribose 5-phosphate

2007-09-18

2007-09-18

Marx, Irene (Department: 1651)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

C435S131000, C435S105000

Reexamination Certificate

active

10652252

ABSTRACT:
The present invention discloses a method of preparing 2-deoxyribose 5-phosphate by reacting glyceraldehyde 3-phosphate and acetaldehyde in the presence of either a microorganism itself which contains 2-deoxyribose-5-phosphate aldolase but substantially no phosphatase or the enzyme derived from the microorganism. The present invention also discloses a method of preparing 2-deoxyribose 5-phosphate by reacting dihydroxyacetone phosphate and acetaldehyde in the presence of either a microorganism itself which contains 2-deoxyribose-5-phosphate aldolase and triose-phosphate isomerase but substantially no phosphatase or the enzymes derived from the microorganism.

REFERENCES:
N. Itoh et al; Appl. Microbiol. Biotechnol, vol. 51, pp. 193-200, 1999.
Carlos F. Barbas, III et al.; J. Am. Chem. Soc., vol. 112, pp. 2013-2014, 1990.
Lihren Chen et al.; J. Am. Chem. Soc., vol. 114, pp. 741-748, 1992.
Wong et al., J. Am. Chem. Soc., vol. 117, pp. 3333-3339 (1995).
Chen et al., J. Am. Chem. Soc., vol. 114, pp. 741-748 (1992).
Barbas et al., J. Am. Chem. Soc., vol. 112, pp. 2013-2014 (1990).

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