Methods and compositions for combinatorial-based discovery...

Details Methods and compositions for combinatorial-based discovery... Methods and compositions for combinatorial-based discovery...

2007-09-11

2007-09-11

Ketter, James (Department: 1636)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S254400, C435S471000

Reexamination Certificate

active

09214699

ABSTRACT:
The present invention provides methods and compositions for producing and screening combinatorial libraries of multimeric proteins. The present invention relies on the use of filamentous fungal heterokaryons that are produced using two or more parent strains into which a population of DNA molecules encoding variants of a multimeric protein have been introduced.

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