Process for preparing enantiomerically pure...

Details Process for preparing enantiomerically pure... Process for preparing enantiomerically pure...

2007-05-08

2007-05-08

Page, Thurman K. (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

C568S700000

Reexamination Certificate

active

10895160

ABSTRACT:
The present invention relates to a method for the chemical separation of the enantiomers of 1,1′-spirobiindane-6,6′-diol derivatives comprising providing a racemic chiral 1,1′-spirobiindane-6,6′-diol derivative, reacting a nonracemic chiral component with the racemic chiral 1,1′-spirobiindane-6,6′-diol derivative to afford a mixture of diastereomeric diesters, separating the mixture of diastereomeric diesters to provide a substantially pure individual diastereomeric diester, and chemically removing the ester groups from the substantially pure individual diastereomeric diester to provide a nonracemic chiral 1,1′-spirobiindane-6,6′-diol derivative.

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