N-sulfonylheterocyclopyrrolyl-alkylamine compounds as...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S314000, C514S368000, C514S414000, C546S121000, C546S172000, C548S126000, C548S453000

Reexamination Certificate

active

11344765

ABSTRACT:
The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of a CNS disorder relating to or affected by the 5-HT6 receptor

REFERENCES:
patent: 6528653 (2003-03-01), Gill et al.
patent: 6730694 (2004-05-01), Beight et al.
patent: 7041695 (2006-05-01), Cole
patent: WO 2004/018479 (2004-03-01), None
patent: WO 2004/018480 (2004-03-01), None
Hegedus et al., “The Chemistry of N-Sulfonyl Enamines,” J. Org. Chem. 1986, 51, 1171-1174.
Riemer, et al., “Influence of the 5-HT6 Receptor on Acetylcholine Release in the Cortex: Pharmacological Characterization of 4-(2-Bromo-6-pyrrolidin-1-ylpyridine-4-sulfonyl)phenylamine, . . . ,” J. Med. Chem. vol. 46, 1273-1276 (2003).
David Wensbo et al.,Tetrahedron Letters,1995, vol. 51, No. 37, 10323-10342.
Joseph B. Blair et al.,Journal of Medicinal Chemistry,1999, vol. 42, No. 6, 1106-1111.

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