Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2007-03-27
2007-03-27
Spector, Lorraine (Department: 1646)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S350000, C530S402000, C536S023500
Reexamination Certificate
active
10063591
ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
REFERENCES:
patent: 5536637 (1996-07-01), Jacobs
patent: 6025156 (2000-02-01), Gwynn et al.
patent: 6124433 (2000-09-01), Falb et al.
patent: 6156500 (2000-12-01), Falb
patent: 6162604 (2000-12-01), Jacob
patent: 6228582 (2001-05-01), Rodier et al.
patent: 6395306 (2002-05-01), Cui et al.
patent: 6414117 (2002-07-01), Levinson
patent: 6465185 (2002-10-01), Goldfine et al.
patent: 6498235 (2002-12-01), Sheppard et al.
patent: 6562343 (2003-05-01), Levinson
patent: 6645499 (2003-11-01), Lal et al.
patent: 6730502 (2004-05-01), Van Hijum et al.
patent: 6737522 (2004-05-01), Sundick et al.
patent: WO 97/38085 (1997-10-01), None
patent: WO 200070049 (2000-11-01), None
Hu et al., Analysis of genomic and proteomic data using advanced literature mining, J. Proteome Res. 2:405-412, 2003.
Wu et al., BNF-1, a novel gene encoding a putative extracellular matrix protein is overexpressed in tumor tissues, Gene 311:105-110, 2003.
Fessler et al., A genomic and proteomic analysis of activation of the human neutrophil by lipoplysaccharide and its mediateion by p38 mitogen-activated protein kinase, J. Biol. Chem. 277(35): 31291-302, Aug. 2002.
Toler et al., Loss of communication in ovarian cancer, Am. J. Obstet. Gynocol., 194:e27-e-31, 2006.
Berner et al., Clinicopathological associations of CD44 mRNA and protein expression in primary breast carcinomas, Histopathol. 42:546-554, 2003.
Oda et al., Expression of MDR1/p-glycoprotein and multidrug resistance-associated protein in childhood solid tumours, Virchows Arch. 430:99-105, 1997.
Papotti et al., Expression of somataostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatice endocrine tumors, Virshows Arch. 440:461-475, 2002.
Klein et al., Selection for Genes Encoding Secreted Proteins and Receptors.Proc. Natl. Acad. Sci., 93:7108-7113 (1996).
Database Search, DNA Sequence Alignments [BLASTN 2.2.1[Jul. 12, 2001], NCBI].
Database Search, Protein Sequence Alignments [BLASTN 2.2.1 [ Jul. 12, 2001], NCBI].
Allman, et al. 1996. BCL-6 expression during B-cell activation.Blood, 87(12):5257-5268.
Chen, et al. 2002. Discordant Protein and mRNA Expression in Lung Adenocarcinomas.Molecular&Cellular Proteomics 1.4, 304-313.
Fu, et al. 1996. Translational regulation of human p53 gene expression.The EMBO Journal, vol. 15, No. 16, pp. 4392-4401.
Gökmen-Polar, et al., Feb. 2001, Elevated Protein Kinase C βII Is an Early Promotive Event in Colon Carcinogenesis,Cancer Research, vol. 61, pp. 1375-1381.
Hanash, S. 2003. Making sense of microarray data to classify cancer.The Pharmacogenomics Jorunal, 3:308-311.
Hanash, S. Mar. 2005. Integrated global profiling of cancer.Nature Reviews, Applied Proteomics Collection, pp. 9-14.
Hancock, W. S. 2004. Do We Have Enouigh Biomarkers?Journal of Proteome Research, 3(4):685.
Haynes, et al., 1998. Proteome analysis: Biological assay or data archive?Electrophoresis, vol. 19, pp. 1862-1871.
Jang A. Hill RP, Sep. 1997. An examination of the affects of hypoxia, acidosis, and glucose starvation on the expression of metastasis-associated genes in murine tumor cells.Clin. Exp. Metastasis 15(5): pp. 469-483.
Konopka, et al. Jun. 1986. Variable Expression of the Translocated c-abl Oncogene in Philadelphia-Chromosome-Positive B-Lymphoid Cell Lines from Chronic Myelogenous Leukemia Patients,National Academy of Sciences of the United States of America, vol. 83, No. 11, pp. 4049-4052.
Ohara, et al. 2001. Directional cDNA library construction assisted by the in vitro recombination reaction.Nucleic Acids Research, vol. 29, No. e22, pp. 1-8.
Powell, et al. Oct. 1998. Expression of cytochrome P4502E1 in human liver: assessment by mRNA, genotype and phenotype.Pharmacogenetics, vol. 5: pp. 411-421.
Vallejo, et al. Dec. 2000. Evidence of tissue-specific, post-transcriptional regulation of NRF-2 expression.Biochimie82(12): 1129-33.
Wang, et al. 1996. mRNA Differential display: Application in the discovery of novel pharmacological targets.Trends Pharmacol. Sci., 17(8):276-279.
Alberts, et al. 1994.Molecular Biology of the Cell, 3rd Edition, pp. 403-404, 453. New York: Garland Publishing.
Alberts, et al. 2002.Molecular Biology of the Cell 4th Edition, pp. 302, 363-364, 379, 435. New York: Garland Publishing.
GENBANK Accession No. AA040433.
Grimaldi, et al. 1989. The t(5;14) chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 gene to the immunoglobulin heavy chain gene.Blood, 73(8):2081-2085.
Gygi, et al. Mar. 1999. Correlation between Protein and mRNA Abundance in Yeast:Molecular and Cellular Biology, 1720-1730.
Hanna, et al. Aug. 1999. HER-2
eu breast cancer predictive testing.Pathology Associates Medical Laboratories.
Hyman et al. Nov. 2002. Impact of DNA Amplication of Gene Expression Patterns.Cancer Research, 62:6240-6245.
Lewin, B. 1994. Oncogenes: Gene Expression and Cancer, Chap. 39, pp. 1196-1201.Genes V. New York: Oxford University Press.
Lewin, B. 1997. Regulation of Transcription, Chap. 29, pp. 847-848.Genes VI. New York: Oxford University Press.
Meeker, et al. 1990. Activation of the interleukin-3 gene by chromosome translocation in acute lymphocytic leukemia with eosinophilia.Blood, 76(2):285-289.
Meric, et al. 2002. Translation Initiation in cancer: A novel target for therapy.Molecular Cancer Therapeutics, 1:971-979.
Ørntoft, et al. 2002. Genome-wide study of gene copy numbers, transcripts, and protein levels in pairs of non-invasive and invasive human transitional cell carcinomas.Molecular&Cellular Proteomics, 1:37-45.
Pollack, et al. 2002. Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors.PNAS, 99(20):12963-12968.
Singleton, et al. 1992. Clinical and pathologic significance of the c-erbB-2 (HER-2
eu)oncogene.Pathol. Annu, 1(27):165-190.
Wi et al., BNF-1, A Novel Gene Encoding a Putative Extracellular Matrix Protein is Overexpressed in Tumor Tissues, Genes 311:105-110, 2003.
Zhigang, et al. 2004. Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues and its potential role in prostate carcinogenesis and progression of prostate cancer.World Journal of Surgical Oncology, 2:13.
Alberts, et al. 1994.Molecular Biology of the Cell, 3rd Edition, pp. 1216-1217. New York: Garland Publishing.
Anderson, et al. 1997. A comparison of selected mRNA and protein abundances in human liver.Electrophoresis, 18:533-537.
Tokunaga, et al. 2000. Application of quantitative RT-PCR using “TaqMan” technology to evaluate the expression of CK 18 mRNA in various cell lines.J. Exp. Clin. Cancer Res., 19(3):375-381.
Labaer, Joshua. 2003. Letter to the editor: Mining the literature and large datasets.Nature Biotechnology, 21(9):976-977.
Lian, et al. 2001. Genomic and proteomic analysis of the myeloid differentiation program.Blood, 98(3):513-524.
Lichtinghagen, et al. 2002. Different mRNA and protein expression of matrix metalloproteinases 2 and 9 abd tissue inhibitor of metalloproteanases 1 in benign and malignant prostate tissue.European Urology, 42:398-406.
Yousef, et al. 2003. Parallel overexpression of seven kallikrein genes in ovarian cancer.Cancer Research, 63:2223-2227.
Abe, et al., “An increased high-mobility group A2 expression level is associated with malignant phenotype in pancreatic exocrine tissue.”Br J Cancer. Dec. 1, 2003;89(11):2104-9. (Abstract Only).
Ando, et al. “Selective apoptosis of natural killer-cell tumours by I-asparaginase.”Br. J. Haematol. Sep. 2005;130(6):860-8. (Abstract Only).
Aust, et al. “Human thyroid carcinoma cell lines and normal thyr
Goddard Audrey
Godowski Paul J.
Grimaldi J. Christopher
Gurney Austin L.
Watanabe Colin K.
Barnes Elizabeth M.
Genentech Inc.
Kaufman Claire M.
Knobbe Martens Olson & Bear LLP
Kresnak Mark T.
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