Non-glycosylated human alpha-fetoprotein, methods of...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

10624380

ABSTRACT:
The invention features non-glycosylated human alpha-fetoprotein, methods of production, and uses thereof.

REFERENCES:
patent: 4692332 (1987-09-01), McMichael
patent: 4873316 (1989-10-01), Meade et al.
patent: 4877610 (1989-10-01), McMichael
patent: 4966753 (1990-10-01), McMichael
patent: 4970071 (1990-11-01), McMichael
patent: 5130415 (1992-07-01), Tecce et al.
patent: 5206153 (1993-04-01), Tamaoki et al.
patent: 5302698 (1994-04-01), Morinaga et al.
patent: 5322775 (1994-06-01), Clark et al.
patent: 5384250 (1995-01-01), Murgita
patent: 5589604 (1996-12-01), Drohan et al.
patent: 5633076 (1997-05-01), DeBoer et al.
patent: 5639940 (1997-06-01), Garner et al.
patent: 5648243 (1997-07-01), Hurwitz et al.
patent: 5652352 (1997-07-01), Lichenstein et al.
patent: 5723585 (1998-03-01), Baker et al.
patent: 5766884 (1998-06-01), Townes et al.
patent: 5827690 (1998-10-01), Meade et al.
patent: 5831141 (1998-11-01), Lubon et al.
patent: 5843705 (1998-12-01), Ditullio et al.
patent: 5843776 (1998-12-01), Tamaoki et al.
patent: 5965528 (1999-10-01), Murgita
patent: 6013857 (2000-01-01), Deboer et al.
patent: 6288034 (2001-09-01), Murgita
patent: 6331611 (2001-12-01), Murgita
patent: 2003/0143237 (2003-07-01), Economou et al.
patent: 0 001 812 (1979-05-01), None
patent: 0 487 229 (1997-09-01), None
patent: 2005866 (1990-01-01), None
patent: WO 86/04241 (1986-07-01), None
patent: WO 93/05774 (1993-04-01), None
patent: WO 94/10199 (1994-05-01), None
patent: WO 95/00637 (1995-01-01), None
patent: WO 96/09377 (1996-03-01), None
patent: WO 96/22787 (1996-08-01), None
patent: WO 00/40693 (2000-07-01), None
patent: WO 01/15709 (2001-03-01), None
Semeiuk et al. Evidence that Immunosuppression is an Intrinsic Property of the Alpha-Fetoprotein Molecule. Immunology or Proteins and Peptides VIII, M.Z. Atassie et al, eds. Plenum Press, New York, 1995, pp. 255-269.
Pucci et al., “Human alpha-Fetoprotein Primary Structure: A Mass Spectrometric Study,” Biochemistry 1991, 30, 5061-5066.
Abramsky et al., “A Role of Alpha-Fetoprotein in Autoimmune Diseases,”Annals New York Academy of Sciences417:108-116 (1983).
Abramsky et al., “Alpha-Fetoprotein Suppresses Experimental Allergic Encephalomyelitis,”Journal of Neuroimmunology2:1-7 (1982).
Aoyagi et al., “Differential Reactivity of Alpha-Fetoprotein with Lectins and Evaluation of its Usefulness in the Diagnosis of Hepatocellular Carcinoma,”Gann75:809-815 (1984).
Bennett et al., “Similarity Between Natural and Recombinant Human Aplha-Fetoprotein as Inhibitors of Estrogen-Dependent Breast Cancer Growth,”Breast Cancer Research and Treatment45:169-179 (1997).
Biddle et al., “Specific Cytoplasmic Alpha-Fetoprotein Binding Protein in MCF-7 Human Breast Cancer Cells and Primary Breast Cancer Tissue,”Breast Cancer Research and Treatment10:279-286 (1987).
Birrer et al., “The Immunology of Alphafetoprotein,”Journal of Tumor Marker Oncology14:55-62 (1999).
Boismenu et al., “Expression of Domains of Mouse Alpha-Fetoprotein inEscherichia coli,” Life Sciences43:673-681 (1988).
Brenner et al., “Immunosuppression of Experimental Autoimmune Myasthenia Gravis by Alpha-Fetoprotein Rich Formation,”Immunology Letters3:163-167 (1981).
Brenner et al., “Influence of Alpha-Fetoprotein on thein Vitroandin VivoImmune Response to Acetylcholine Receptor,”Annals New York Academy of Sciences377:208-221 (1981).
Brenner et al., “Inhibitory Effect of Alpha-Fetoprotein on the Binding of Myasthenia Gravis Antibody to Acetylcholine Receptor,”Proc. Natl. Acad. Sci. USA77:3635-3639 (1980).
Buamah et al., “Serum Alpha-Fetoprotein Heterogeneity as a Means of Differentiating Between Primary Hepatocellular Carcinoma and Hepatic Secondaries,”Clinica. Chimica. Acta.139:313-316 (1984).
Buschman et al., “Experimental Myasthenia Gravis Induced in Mice by Passive Transfer of Human Myasthenic Immunoglobulin,”Journal of Neuroimmunology13:315-330 (1987).
Caturla et al., “The Thyroid Hormone Down-Regulates the Mouse Alpha-Foetoprotein Promoter,”Molec. and Cell. Endocrin.135:139-145 (1997).
Cohen et al., “Suppression by Alpha-Fetoprotein of Murine Natural Killer Cell Activity Stimulatedin Vitroandin Vivoby Interferon and Interleukin 2,”Scand. J. Immunol.23:211-223 (1986).
Dattwyler et al., “Binding of Alpha-Foetoprotein to Murine T Cells,”Nature256:656-657 (1975).
Dudich et al., “Growth-Regulative Activity of Human Alpha-Fetoprotein for Different Types of Tumor and Normal Cells,”Tumor Biology19:30-40 (1998).
Galarneau et al., “The Alpha1-Fetoprotein Locus is Activated by a Nuclear Receptor of theDrosophilaFTZ-F1 Family,”Molec. and Cell. Biol.16:3853-3865 (1996).
Gershwin et al., “The Influence of Alpha-Fetoprotein on Moloney Sarcoma Virus Oncogenesis: Evidence for Generation of Antigen Nonspecific Suppressor T Cells,”The Journal of Immunology121:2292-2297 (1978).
Gibbs et al., “Structure, Polymorphism, and Novel Repeated DNA Elements Revealed by a Complete Sequence of the Human Alpha-Fetoprotein Gene,”Biochemistry26:1332-1343 (1987).
Giuliani et al., “Synthesis and Characterization of a Recombinant Fragment of Human Alpha-Fetoprotein with Antigenic Selectivity Versus Albumin,”Protein Engineering2:605-610 (1989).
Glazier et al., “Graft-Versus-Host Disease in Cyclosporin A-Treated Rats After Syngeneic and Autologous Bone Marrow Reconstitution,”J. Exp. Med.158:1-8 (1983).
Goidl et al., “Studies on the Mechanisms of Alpha-Fetoprotein Induction of Immune Suppressive Activity,”from Developmental Immunobiology, Proceedings of the Fifth Irwin Strasburger Memorial Seminar on Immunologyeds. Siskind et al., 35-55 (1979).
Hamel et al., “Phenotype and Function of Bone-Marrow-Derived T- and Non-T-Cells Activatedin Vitroby Alpha-Fetoprotein,”Biological Activities of Alpha1-Fetoproteineds. Mizejewski et al. 1:167-177 (1987).
Heyward et al., “Early Detection of Primary Hepatocellular Carcinoma by Screening for Alpha-Fetoprotein in High-Risk Families,”The Lancet2:1161-1162 (1983).
Hooper et al., “Human AFP Inhibits Cell Proliferation and NK-Like Cytotoxic Activity Generated in Autologous, but not in Allogeneic Mixed Lymphocyte Reactions,”Biological Activities of Alpha1-Fetoproteineds. Mizejewski et al. 2:183-197 (1989).
Hooper et al., “Regulation of Murine T-Cell Responses to Autologous Antigens by Alpha-Fetoprotein,”Cellular Immunology63:417-425 (1981).
Hooper et al., “Selective Inhibition of Murine T-Cell Proliferation and Lymphokine-Activated Natural Killer Cell Function by Alpha-Fetoprotein,”Biological Activities of Alpha1-Fetoproteineds. Mizejewski et al. 1:153-165 (1987).
Hooper et al., “Suppression of Primary and Secondary Autologous Mixed Lymphocyte Reactions by Murine Alphafetoprotein,”Oncodevelopmental Biology and Medicine3:151-160 (1982).
Hoskin et al., “Analysis of Pregnancy-Associated Immunoregulatory Pathways,”Alpha-Fetoprotein and Congenital Disorders59-78 (1985).
Hoskin et al., “In VitroActivation of Bone Marrow-Derived T-and Non-T-Cell Subsets by Alpha-Fetoprotein,”Cellular Immunology96:163-174 (1985).
Hoskin et al., “Specific Maternal Anti-Fetal Lymphoproliferative Responses and Their Regulation by Natural Immunosuppressive Factors,”Clin. Exp. Immunol.76:262-267 (1989).
Innis et al., “Amplification of Alpha-Fetoprotein Complementary DNA by Insertion into a Bacterial Plasmid,”Archives of Biochemistry and Biophysics195:128-135 (1979).
Ishiguro et al., “Serum Alpha-Fetoprotein Subfractions in Patients with Primary Hepatoma or Hepatic Metastasis of Gastric Cancer,”Cancer55:156-159 (1985).
Jacobson et al., “Inhibition of Estrogen-Dependent Breast Cancer Growth by a Reaction Product of Alpha-Fetoprotein and Estradiol,”Cancer Research50:

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Non-glycosylated human alpha-fetoprotein, methods of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Non-glycosylated human alpha-fetoprotein, methods of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Non-glycosylated human alpha-fetoprotein, methods of... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3740650

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.