Signal processing method in autoradiography

Details Signal processing method in autoradiography Signal processing method in autoradiography

1984-01-06

1989-09-19

Smith, Jerry

Boots, shoes, and leggings

382 6, G01T 100, G01N 3350, G01N 2726, G21H 500

Patent

active

048687464

ABSTRACT:
A signal processing method in autoradiography employing a radiosensitive material for the purpose of obtaining information on one dimensional location of radioactively labeled substances distributed in at least one dimensional direction on a support medium, in the form of symbol, numeral or combination thereof, comprising the steps of obtaining a digital signal corresponding to the autoradiograph on a radiosensitive material, by exposing said radiosensitive material to radiation emitted by said radioactively labeled substances on the support medium determining one dimensional scanning line relative to said digital signal; and detecting sampling points on said scanning line, comprising and identifying the positions of said sampling points detected on said scanning line among resolved rows for determining the base sequence of labeled substances.

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Sanger, F. et al., "DNA Sequencing with Chain-Terminating Inhibitors" Proc. Natl. Acad. Sci. U.S.A., vol. 74, No. 12, pp. 5463-5467, 12/1977.
Smith, L. et al., "Fluorescence Detection in Automated DNA Sequence Analysis", Nature, vol. #321, 6/12/1986, pp. 674-678.

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