Process for production of...

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

Reexamination Certificate

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C544S386000

Reexamination Certificate

active

10535705

ABSTRACT:
This invention relates to a method for producing 1-[2-(benzimidazol-2-ylthio)ethyl]piperazine (5) or its salt by the following reaction scheme:This invention enables efficient production of 1-[2-(benzimidazol-2-ylthio) ethyl]piperazine or its salt which is an intermediate in the production of a cyclic diamine compound which is useful as a ACAT inhibitor.

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U.S. Appl. No. 10/535,705, filed May 20, 2005, Shibuya et al.
Rashmi Rastogi, et al., “Synthesis of 2-Substituted Thiobenzimidazoles as Potential Anthelminthics”, Arch. Pharm. (Weinheim), XP-002963488, vol. 316, No. 7, 1983, pp. 638-643.

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