Processes for preparing fluoroarenes from haloarenes

Details Processes for preparing fluoroarenes from haloarenes Processes for preparing fluoroarenes from haloarenes

2007-04-10

2007-04-10

Barts, Samuel (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Halogen containing

C570S170000

Reexamination Certificate

active

11244980

ABSTRACT:
Processes for preparing fluoroarenes are provided. The processes include contacting a compound having an unactivated aryl group with a source of fluoride or bifluoride in the presence of a transition metal a ligand.

REFERENCES:
patent: 3398203 (1968-08-01), Olson
patent: 4394527 (1983-07-01), Fischer, Jr. et al.
patent: 5315043 (1994-05-01), Fernandez et al.
patent: 5756834 (1998-05-01), Pasenok et al.
patent: 5965775 (1999-10-01), Pfirmann et al.
patent: 6087543 (2000-07-01), Subramanian
patent: 6166273 (2000-12-01), Subramanian
patent: 6469224 (2002-10-01), Nobori et al.
patent: 6784327 (2004-08-01), Yoneda et al.
patent: WO 01/096267 (2001-12-01), None
Vlasov et al., Nucleophilic Substitution of the Nitro Group, Fluorine And Chlorine in Aromatic Compounds, Russian Chem. Review, 2003, vol. 72:681-703.
Adams et al., Nucleophilic Routes to Selectively Fluorinated Aromatics, Chem. Soc. Rev., 1999, vol. 28:225-231.
V. Grushin et.al., Palladium Fluoride Complexex: One More Step Toward Metal-Mediated C-F Bond Formation, Chem. Eur. J., 2002, vol. 8:1006-1014.
Bunnett et al., Aromatic Nucleophilic Substitution Reactions, Chem. Review, 1951, pp. 273-412.
Kageyama et. al., Sulfonyl Chloride as A Disposable Electron Withdrawing Substituent in Halex Fluorinations, Journal of Fluorine Chemistry, 2000, vol. 101:85-89.
Plevey et. al., Fluorination with Complex Metal Fluorides Part II. The Fluorination of Benzene, Tetrahydrofuran and Cyclohexanone with Silver Difuoride and Potassium Tetrafluoroargentate, Journal of Fluorine Chemistry, 1973, vol. 3:259-266.
Hansch et. al., Aromatic Substituent Constants for Structure-Activity Correlations, Journal of Medicinal Chemistry, 1973, vol. 16:1207-1216.
McDaniel et. al., An Extended Table of Hammett Substituent Constants Based on the Ionization of Substituted Benzoic Acids, 1957, vol. 23:420-427.
Ebert et. al., Direct Formation of (Haloaryl) Copper Nucleophiles from Haloiodobenzenes and Active Copper, J. Org. Chem., 1995, vol. 60:2361-2364.

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