Non-fiber extract of psyllium with anti-tumorigenic effects...

Details Non-fiber extract of psyllium with anti-tumorigenic effects... Non-fiber extract of psyllium with anti-tumorigenic effects...

2007-03-27

2007-03-27

Tate, Christopher (Department: 1661)

Drug, bio-affecting and body treating compositions

Plant material or plant extract of undetermined constitution...

Containing or obtained from plantago

Reexamination Certificate

active

10375401

ABSTRACT:
A composition comprising a non-fiber organic extract of psyllium which is anti-tumorigenic is described. The composition both restores gap junctional intercellular communication (GJIC) and inhibits anchorage independent growth of mammalian cells which have been transformed with the ras oncogene. The composition is a useful chemotherapy and chemopreventative agent. The composition was identified using a novel method for determining the anti-tumorigenic potential of a compound or composition.

REFERENCES:
patent: 6287609 (2001-09-01), Marlett et al.
Alabaster et al.; “Dietary fiber and the chemopreventive modelation of colon carcinogenesis,” Mutation Research 350 (1996) p. 185-197.
The Internet website http://www.wellfx.com/InfoBase/herb—Psyllium—html (2 pages).
Gura, T. “Systems for Identifying New Drugs Are Often Faulty,” Science; (1997) vol. 278, pp. 1041-1042.
Sparreboom et al. “Herbal Remedies in the United States: Potential Adverse Interactions with Anticancer Agents,” Journal of Clinical Oncology, vol. 22; No.12; Jun. 18, 2004; pp. 2489-2503. 15 pages total.

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